Treatment for prostate cancer typically leaves a patient exhausted. Such tiredness isn't your everyday kind you feel after a long day; this is out and out bone-weary exhaustion that makes you irritable and depressed. Rest does not always refresh the patient and sometimes makes the depression even worse. Fatigue is common in patients who have gone though a cancer treatment, but they shouldn't be to rest. Rest doesn't work usually.
Many prostate cancer patients resist any prompts to get them out of bed. What they need is physical activity to bolster their energy, but they feel so tired that moving or any physical activity seems overwhelming. After spending much of their time in bed during treatment, endurance and muscle strength wane. A patient sorely needs to move around a little to so as to recoup some strength, but if his muscles have wasted to any extent, it is sensible for a physical therapist to assist him maintain strength.
To start off, therapy can be conducted in bed; later on it would continue on his own feet and even outdoors. A change in scenery can work wonders in lifting spirits and fighting fatigue and depression.
Health benefits of exercise for prostate cancer patient's include vascular improvement, easing of anxiety and depression, and helping regain lost muscular mass. The American Cancer Society claims that exercise helps prevents cancer recurrence and may prevent some cancers from taking hold in the body at all.
Adults are recommended to get at least 30 minutes of physical per day three times a week. Children and teens need 60 minutes of physical activity at least 5 times per week to keep overall health good.
Socializing is also key for a prostate cancer patient. Consider visits outside the patient's bedroom or outdoors, so the patient has the chance to walk a bit. Children usually have a good effect on adults; bring the kids along if you visit. For some, attending church may also give them strength.
For information on prostate cancer symptoms and prostate treatment surgery, visit Medopedia.com
Article Source: http://EzineArticles.com/?expert=Antoinette_Boulay
Monday, November 10, 2008
Sunday, November 2, 2008
New Throat Cancer Treatment
Throat cancer is one of the cancers which occur in the throat. This is disease is found with different names like vocal cord cancer, throat cancer, laryngeal cancer, cancer of the glottis. This is the cancer which is found in both men and women.
The throat cancer is the cancer which appears in the upper part of the throat. It is the cancer which appears in the throat that is vocal cords, voice box (larynx), or other areas of the throat. This cancer spreads not only occurs in the other parts of the throat also. This is cancer which can occur in both men and women. This cancer involves the uncontrolled growth of abnormal cells that have mutated from normal tissues. This growth can kill when these cells prevent normal function of vital organs or spread throughout the body, damaging essentials systems.
For more information meet: dr jack
This throat cancer has some alternate names like vocal cord cancer, laryngeal cancer, cancer of the glottis, cancer of the pharynx, vocal cord cancer and others. This cancer as it occurs to the throat and the parts related to it so it is named after it. This cancer also occurs when the normal cells undergo a transformation whereby they grow and multiply without normal controls. This cancer involves tumors on the tonsils, vocal cords, voice box (larynx) and at the base of the tongue.
The main cause for the exposure for this cancer is the consumption of the tobacco that plays a significant role in many of the cases. The causes for this cancer are the heavy smoking of cigarettes, chewing tobacco, excessive use of alcohol is also one of the causes for its occurrence. But if the man is addicted to both smoking and consuming alcohol then he is at higher risk of getting the disease. But this is more occurred in men than women. This disease can occur to any age but mainly occurs to the age group who is above 45 of age. This can be controlled with herbal products Some of the other factors for the occurrence of this cancer are the enlargement of the thyroid gland called chronic goiter. This cause may be due to the radiation exposure and the family history of cancer or the genetic predisposition.
The symptoms of the hoarseness, sore throat, neck pain, difficulty in swallowing, swelling in the neck, unintentional weight loss, cough, coughing up blood, abnormal breathing sounds, numbness or the paralyses of the muscles in the face, swelling of the jaw, shortness of breath, chest pain and many other reasons also. This cancer also has some of the common symptoms like fever, chills, night sweats, weight loss, loss of appetite, fatigue, malaise.
The above symptoms are not to be considered as a serious one as these may also be the causes for some of the common health upsets also. But if the person is adult then he has to undergo a medical checkup and have a take care of his health.
The signs and tests can be done when an examination of the neck and the throat may show the cancer of the throat. The symptom may appear bloody or lump on the throat which appears on the outside of the neck. Biopsy and the analysis of tissues that appear abnormal may conform the presence of the cancer tumor.
If you experience any of the above throat cancer symptoms it is advised that you see your healthcare provider for a more thorough check so the proper diagnose and treatment can be apply in the initial stage.
the best way of preventing this cancer is to quit smoking and preventing the consumption of tobacco. Many cancers can be prevented by avoiding risk factors such as excessive exposure to sunlight and heavy drinking. We should cultivate a habit of taking healthy diet that is the consumption of fresh vegetables and fruits. Keeping the health fit by doing the exercises, meditation, yogasanas, cultivation of morning jog or walk, having the nutritious food in the diet, protecting ourselves from bad atmosphere may make us to be free from the diseases also.
Some people at high risk for developing certain cancers can take medication to reduce their risk. But yet the treatment must be aimed at destruction of the cancer and prevention of its spread to other parts of the body. The treatment of the cancer depends on certain issues like the age of the patient, general health condition, the size of the tumor, extent of the cancer and others.
This is the cancer which may be found at its advanced stage. So it is an urge need that the patient should be careful while choosing the correct physician for his treatment. This treatment is aimed at destruction of the cancer and prevention of spread of the cancer to the other parts of the body. The earlier it is diagnosed the earlier it is treated.
Treatment is aimed at destruction of the cancer and prevention of spread of the cancer to other parts of the body. The earlier throat cancer is diagnosed, the better the prospect of recovery. If the treatment is not given then it can grow and can cause to death. So it is better to get treated at its initial stage. The treatment needs long term recovery but if have a hope of conquering it then you can have it. You should be mentally firmed and be prepared to achieve in curing it.
The people who come to our center have a hope of curing the disease and becoming healthy. We support you with this attitude of yours as we use the alternative supplements which are natural and cure the disease with no side effects with miraculous improvements in your health condition. We make you feel ease and get away from your suffer.
Article Source: http://www.articlesbase.com/alternative-medicine-articles/new-throat-cancer-treatment-59444.html
The throat cancer is the cancer which appears in the upper part of the throat. It is the cancer which appears in the throat that is vocal cords, voice box (larynx), or other areas of the throat. This cancer spreads not only occurs in the other parts of the throat also. This is cancer which can occur in both men and women. This cancer involves the uncontrolled growth of abnormal cells that have mutated from normal tissues. This growth can kill when these cells prevent normal function of vital organs or spread throughout the body, damaging essentials systems.
For more information meet: dr jack
This throat cancer has some alternate names like vocal cord cancer, laryngeal cancer, cancer of the glottis, cancer of the pharynx, vocal cord cancer and others. This cancer as it occurs to the throat and the parts related to it so it is named after it. This cancer also occurs when the normal cells undergo a transformation whereby they grow and multiply without normal controls. This cancer involves tumors on the tonsils, vocal cords, voice box (larynx) and at the base of the tongue.
The main cause for the exposure for this cancer is the consumption of the tobacco that plays a significant role in many of the cases. The causes for this cancer are the heavy smoking of cigarettes, chewing tobacco, excessive use of alcohol is also one of the causes for its occurrence. But if the man is addicted to both smoking and consuming alcohol then he is at higher risk of getting the disease. But this is more occurred in men than women. This disease can occur to any age but mainly occurs to the age group who is above 45 of age. This can be controlled with herbal products Some of the other factors for the occurrence of this cancer are the enlargement of the thyroid gland called chronic goiter. This cause may be due to the radiation exposure and the family history of cancer or the genetic predisposition.
The symptoms of the hoarseness, sore throat, neck pain, difficulty in swallowing, swelling in the neck, unintentional weight loss, cough, coughing up blood, abnormal breathing sounds, numbness or the paralyses of the muscles in the face, swelling of the jaw, shortness of breath, chest pain and many other reasons also. This cancer also has some of the common symptoms like fever, chills, night sweats, weight loss, loss of appetite, fatigue, malaise.
The above symptoms are not to be considered as a serious one as these may also be the causes for some of the common health upsets also. But if the person is adult then he has to undergo a medical checkup and have a take care of his health.
The signs and tests can be done when an examination of the neck and the throat may show the cancer of the throat. The symptom may appear bloody or lump on the throat which appears on the outside of the neck. Biopsy and the analysis of tissues that appear abnormal may conform the presence of the cancer tumor.
If you experience any of the above throat cancer symptoms it is advised that you see your healthcare provider for a more thorough check so the proper diagnose and treatment can be apply in the initial stage.
the best way of preventing this cancer is to quit smoking and preventing the consumption of tobacco. Many cancers can be prevented by avoiding risk factors such as excessive exposure to sunlight and heavy drinking. We should cultivate a habit of taking healthy diet that is the consumption of fresh vegetables and fruits. Keeping the health fit by doing the exercises, meditation, yogasanas, cultivation of morning jog or walk, having the nutritious food in the diet, protecting ourselves from bad atmosphere may make us to be free from the diseases also.
Some people at high risk for developing certain cancers can take medication to reduce their risk. But yet the treatment must be aimed at destruction of the cancer and prevention of its spread to other parts of the body. The treatment of the cancer depends on certain issues like the age of the patient, general health condition, the size of the tumor, extent of the cancer and others.
This is the cancer which may be found at its advanced stage. So it is an urge need that the patient should be careful while choosing the correct physician for his treatment. This treatment is aimed at destruction of the cancer and prevention of spread of the cancer to the other parts of the body. The earlier it is diagnosed the earlier it is treated.
Treatment is aimed at destruction of the cancer and prevention of spread of the cancer to other parts of the body. The earlier throat cancer is diagnosed, the better the prospect of recovery. If the treatment is not given then it can grow and can cause to death. So it is better to get treated at its initial stage. The treatment needs long term recovery but if have a hope of conquering it then you can have it. You should be mentally firmed and be prepared to achieve in curing it.
The people who come to our center have a hope of curing the disease and becoming healthy. We support you with this attitude of yours as we use the alternative supplements which are natural and cure the disease with no side effects with miraculous improvements in your health condition. We make you feel ease and get away from your suffer.
Article Source: http://www.articlesbase.com/alternative-medicine-articles/new-throat-cancer-treatment-59444.html
New Treatment Options for Breast Cancer
Although surgery is the most effective (and hence, the most widely used) breast cancer treatment method, there are several other ways of dealing with the disease, some are more powerful than the others. These include radiation therapy, chemotherapy or hormonal therapy, each of them with their own assets and downsides.
Most of them however are used in combination with surgery for best effects, either prior to it, in order to reduce the size of the tumor or after the operation, in order to remove any remaining cancerous cells. For a better understanding of these alternative treatment methods for breast cancer, we'll take a closer look at each, explaining how they work and in what cases they might prove useful.
Radiation Therapy
Radiation therapy uses powerful gamma rays (x-rays) which target the specific area that needs to be treated with high precision. Usually, radiation therapy is performed after surgery, to destroy any cancer cells that have not been removed or the ones that formed up where the tumor was removed. Although it can't be used as, a treatment on its own, radiation therapy is one of the most accepted post-surgery methods of breast conserving therapy (BCT) and has a high chance of stopping the cancer from recurring.
As with all treatments involving x-rays, there are some downsides to radiation therapy. First, in order to wipe out the cancerous cells that might have formed (or remained) in the area where the tumor was removed from, the x-rays will eventually damage some of the healthy tissue too. Although the process is highly precise, the rays cannot make a difference between cancerous and normal cells, so they "burn" them together.
Chemotherapy
Chemotherapy involves the administration of drugs that kill the cancer cells or stop them from growing. Most chemotherapy medications are given through an intravenous line, although some are administered in pill form. Chemotherapy is a harsh regime, which often makes people feel more ill than the illness they are suffering from; however, it has been proved very effective.
Chemotherapy is a great treatment method to use both prior and after surgery. With the help of this method, you can virtually contract the cancerous tumor before the actual surgery, making it easier and less complex to remove. In addition, chemotherapy is used in the same sense as radiation therapy after the surgical intervention, to stop the diseased cells to recur.
Chemotherapy is administered usually in cycles where each cycle consists of a period of intensive treatment that lasts for a few days or weeks followed by a week of recovery. Most patients with breast cancer have two to four cycles of chemotherapy to start with before tests are performed to see what effects it has had on the cancer.
Chemotherapy is different to radiation as it can treat the whole body with the potential of finding other tumor cells that have migrated from the breast and surrounding area. Many people are familiar with chemotherapy's side effects although the side effects do depend upon drugs to treat the patient.
The most common side effects are loss of hair, loss of appetite, fatigue, vomiting and low blood cell count making the patient more susceptible to infections, feeling sick or tired. Many notice that they bleed more than usual, especially from gums, sores and small scrapes etc.
There are three different chemotherapy strategies are used in breast cancer:
Adjuvant chemotherapy this is given to patients who have undergone curative treatment for breast cancer such as radiation or surgery. In order to decrease the possibility of the breast cancer recurrence, this treatment is given.
Pre-surgical chemotherapy this is given to shrink a large tumor and/or to kill any stray cancerous cells. This will also increase the chance that the surgery will kill the cancer completely.
Regular chemotherapy this is given routinely to people who have breast cancer that has spread beyond the breast or the surrounding local area.
Hormonal therapy may also be given, as many breast cancers such as those that have ample estrogens or progesterone receptors are sensitive to changes in hormones.
Tamoxifen Breast Cancer Treatment
Those women who are genetically at high risk of developing breast cancer may benefit from tamoxifen as it has previously been seen to decrease the incidence of the disease occurring. Raloxifene, which is used to treat osteoporosis, is now being studied for treating breast cancer.
In some breast cancer cases, a woman's natural hormones are suppressed with drugs whereas other patients find benefits by adding hormones. Tamoxifen for instance is currently the most commonly prescribed effective hormone treatment. It can be used for treating breast cancer and in the prevention of breast cancer. Tamoxifen has few side effects and can considerably improve the life span of those women who have advanced cases of breast cancer.
Fulvestrant Breast Cancer Treatment
A further treatment, Fulvestrant has recently been approved in the USA. It is planned to be used for treating hormone receptor positive metastastic breast cancer in women who have been through the menopause. It is given following antiestrogen therapy.
Monoclonal Breast Cancer Treatment
Another treatment known as monoclonal is antibodies that are antagonistic against the proteins, which are in or around cancer cells. They recognise an invader such as a cancer cell and attack it. This antibody therapy is currently being investigated holds out a lot of hope for breast cancer sufferers.
Excessive alcohol intake and obesity following menopause can increase the risk of developing breast cancer although this increase is slight. Those physically active women have a lower risk.
Preventative or Prophylactic Mastectomies
More and more women who are at a high risk of developing breast cancer are having preventative or prophylactic mastectomies to avoid them developing breast cancer.
The main risk factors for women to develop breast are age, sex and genetics. Women can do nothing about some risks so preventing death caused due to breast cancer is recommended with regular screening.
Women should undertake regular screening including self-examination, mammography and clinical breast examinations.
I hope that reading the above information was both enjoyable and educational for you. That's how things stand right now. Keep in mind that any subject can change over time, so be sure you keep up with the latest news.
Article Source: http://www.articlesbase.com/diseases-and-conditions-articles/new-treatment-options-for-breast-cancer-64000.html
Most of them however are used in combination with surgery for best effects, either prior to it, in order to reduce the size of the tumor or after the operation, in order to remove any remaining cancerous cells. For a better understanding of these alternative treatment methods for breast cancer, we'll take a closer look at each, explaining how they work and in what cases they might prove useful.
Radiation Therapy
Radiation therapy uses powerful gamma rays (x-rays) which target the specific area that needs to be treated with high precision. Usually, radiation therapy is performed after surgery, to destroy any cancer cells that have not been removed or the ones that formed up where the tumor was removed. Although it can't be used as, a treatment on its own, radiation therapy is one of the most accepted post-surgery methods of breast conserving therapy (BCT) and has a high chance of stopping the cancer from recurring.
As with all treatments involving x-rays, there are some downsides to radiation therapy. First, in order to wipe out the cancerous cells that might have formed (or remained) in the area where the tumor was removed from, the x-rays will eventually damage some of the healthy tissue too. Although the process is highly precise, the rays cannot make a difference between cancerous and normal cells, so they "burn" them together.
Chemotherapy
Chemotherapy involves the administration of drugs that kill the cancer cells or stop them from growing. Most chemotherapy medications are given through an intravenous line, although some are administered in pill form. Chemotherapy is a harsh regime, which often makes people feel more ill than the illness they are suffering from; however, it has been proved very effective.
Chemotherapy is a great treatment method to use both prior and after surgery. With the help of this method, you can virtually contract the cancerous tumor before the actual surgery, making it easier and less complex to remove. In addition, chemotherapy is used in the same sense as radiation therapy after the surgical intervention, to stop the diseased cells to recur.
Chemotherapy is administered usually in cycles where each cycle consists of a period of intensive treatment that lasts for a few days or weeks followed by a week of recovery. Most patients with breast cancer have two to four cycles of chemotherapy to start with before tests are performed to see what effects it has had on the cancer.
Chemotherapy is different to radiation as it can treat the whole body with the potential of finding other tumor cells that have migrated from the breast and surrounding area. Many people are familiar with chemotherapy's side effects although the side effects do depend upon drugs to treat the patient.
The most common side effects are loss of hair, loss of appetite, fatigue, vomiting and low blood cell count making the patient more susceptible to infections, feeling sick or tired. Many notice that they bleed more than usual, especially from gums, sores and small scrapes etc.
There are three different chemotherapy strategies are used in breast cancer:
Adjuvant chemotherapy this is given to patients who have undergone curative treatment for breast cancer such as radiation or surgery. In order to decrease the possibility of the breast cancer recurrence, this treatment is given.
Pre-surgical chemotherapy this is given to shrink a large tumor and/or to kill any stray cancerous cells. This will also increase the chance that the surgery will kill the cancer completely.
Regular chemotherapy this is given routinely to people who have breast cancer that has spread beyond the breast or the surrounding local area.
Hormonal therapy may also be given, as many breast cancers such as those that have ample estrogens or progesterone receptors are sensitive to changes in hormones.
Tamoxifen Breast Cancer Treatment
Those women who are genetically at high risk of developing breast cancer may benefit from tamoxifen as it has previously been seen to decrease the incidence of the disease occurring. Raloxifene, which is used to treat osteoporosis, is now being studied for treating breast cancer.
In some breast cancer cases, a woman's natural hormones are suppressed with drugs whereas other patients find benefits by adding hormones. Tamoxifen for instance is currently the most commonly prescribed effective hormone treatment. It can be used for treating breast cancer and in the prevention of breast cancer. Tamoxifen has few side effects and can considerably improve the life span of those women who have advanced cases of breast cancer.
Fulvestrant Breast Cancer Treatment
A further treatment, Fulvestrant has recently been approved in the USA. It is planned to be used for treating hormone receptor positive metastastic breast cancer in women who have been through the menopause. It is given following antiestrogen therapy.
Monoclonal Breast Cancer Treatment
Another treatment known as monoclonal is antibodies that are antagonistic against the proteins, which are in or around cancer cells. They recognise an invader such as a cancer cell and attack it. This antibody therapy is currently being investigated holds out a lot of hope for breast cancer sufferers.
Excessive alcohol intake and obesity following menopause can increase the risk of developing breast cancer although this increase is slight. Those physically active women have a lower risk.
Preventative or Prophylactic Mastectomies
More and more women who are at a high risk of developing breast cancer are having preventative or prophylactic mastectomies to avoid them developing breast cancer.
The main risk factors for women to develop breast are age, sex and genetics. Women can do nothing about some risks so preventing death caused due to breast cancer is recommended with regular screening.
Women should undertake regular screening including self-examination, mammography and clinical breast examinations.
I hope that reading the above information was both enjoyable and educational for you. That's how things stand right now. Keep in mind that any subject can change over time, so be sure you keep up with the latest news.
Article Source: http://www.articlesbase.com/diseases-and-conditions-articles/new-treatment-options-for-breast-cancer-64000.html
What are the Risk Factors for Breast Cancer?
Breast cancer is a largely unknown disease until today, despite the fact that it affects almost ten percent of the women above the age of forty years all over the world. The causes of this killer cancer are not known even after decades of research into it. Similarly it is unknown why some women have higher chances of getting breast cancers than others.
Though the causative factors are not known, some risk factors have been identified. There is no medical proof why these factors make the disease more probable, but this is a study of observation. In a vast cross-section of women with the observed risk factors, it has been found that the chances of getting breast cancers are very high.
The various risk factors for breast cancer are as follows:-
(1) Family History of Breast Cancer
If a near relative like a mother or a sister has had breast cancer, then there is a very high chance that the cancer will occur sometime in life. This propensity is observed even if far relatives such as cousins and aunts have had breast cancer, though the chances are lesser as the relatives are more removed. Even if a male relative has had breast cancer or prostate cancer, then there is a chance of getting breast cancer. This clearly indicates that breast cancer runs through family lines through inheritance. Certainly the chances are very high if more than one family member has had breast cancer.
(2) Personal History of Breast Cancer
If a woman has had breast cancer in the past, then there is a great chance that the breast cancer may recur. This is true even if the cancer had been removed in its benign stage itself. Sometimes the cancer cells spread into the nearby lymph. This makes a possibility that the cancer will occur in the opposite breast. In fact, women who have had cancer in one breast have 50 to 75% more chances of developing the cancer in the other breast.
(3) Diseases of the Breast
Several breast diseases can increase the chances of having breast cancer. Changes in the cells of the breasts can lead to atypical hyperplasia. This condition can cause a three to fourfold increase in the possibility of getting breast cancer in the later years. This risk also exists if the atypical hyperplasia has occurred in other women of the family. Another such condition is the benign breast tumor condition known as fibro adenoma. However, women with fibrocystic breasts generally do not have any added vulnerability to breast cancer. Yet, such conditions could make the breasts lumpy and hide the real tumors (if any) during mammography.
(4) Lifestyle
In today’s world, lifestyle is the single largest contributing factor for the proliferation of breast cancer among women. Several elements of the lifestyle have been found to be directly accordant with the prevalence of breast cancer. Smoking and alcoholism in women are among the chief factors. Even diet has been pointed out as an important risk factor. Women who consume a diet with more high-cholesterol fats in them have higher chances of breast cancer. At the same time leading a sedentary lifestyle without indulging much in physical activity are also potentially dangerous.
(5) Radiation
It has been found that women who undergo radiation therapies in their chest region at a young age have an increased risk of developing breast cancer in their later lives. Radiation therapy is generally prescribed for women with conditions like Hodgkin’s disease or non-Hodgkin’s lymphoma. So women who have undergone such treatments may get breast cancer in their later years.
(6) Hormonal Imbalances There are several factors that can change the hormone balance of the body. Some of them are:- a) Beginning the menstrual cycle early, i.e. before the age of twelve years, b) Having the first pregnancy after the age of thirty years, c) Having no pregnancy at all, d) Having a late menopause. All these conditions can increase the level of estrogen in the body. This increases the risk of getting breast cancer to a mild extent. Apart from that women who take regular birth control pills, breast enhancement supplements, antidepressants and antihistamines and hormone modifying supplements stand at a higher risk to get breast cancers.
The above are the major risk factors for breast cancers. But since the study on breast cancers is not yet complete, the above is by no means a complete list. There are several other indications of breast cancers, like breast implant operations; but these have not yet been confirmed. The implants used in the earlier days were made of silicone gels. These were riskier in terms of breast cancer. However, nowadays the silicone gel implants have been replaced by saline implants. This has reduced the risk to a great extent.
It must be also noted that women have much higher chances of getting breast cancer than men. In fact, most people think that breast cancer is a disease that affects only women. This is not true. Men also get breast cancers, but to a much lesser degree than women. Also, age is a very important factor. The chances of getting breast cancer are much higher when the woman has crossed the age of 50 years.
Read more about the Breast Cancer Information and other breast care issues at http://www.mysecrethealth.com
Article Source: http://www.articlesbase.com/women's-issues-articles/what-are-the-risk-factors-for-breast-cancer-101136.html
Though the causative factors are not known, some risk factors have been identified. There is no medical proof why these factors make the disease more probable, but this is a study of observation. In a vast cross-section of women with the observed risk factors, it has been found that the chances of getting breast cancers are very high.
The various risk factors for breast cancer are as follows:-
(1) Family History of Breast Cancer
If a near relative like a mother or a sister has had breast cancer, then there is a very high chance that the cancer will occur sometime in life. This propensity is observed even if far relatives such as cousins and aunts have had breast cancer, though the chances are lesser as the relatives are more removed. Even if a male relative has had breast cancer or prostate cancer, then there is a chance of getting breast cancer. This clearly indicates that breast cancer runs through family lines through inheritance. Certainly the chances are very high if more than one family member has had breast cancer.
(2) Personal History of Breast Cancer
If a woman has had breast cancer in the past, then there is a great chance that the breast cancer may recur. This is true even if the cancer had been removed in its benign stage itself. Sometimes the cancer cells spread into the nearby lymph. This makes a possibility that the cancer will occur in the opposite breast. In fact, women who have had cancer in one breast have 50 to 75% more chances of developing the cancer in the other breast.
(3) Diseases of the Breast
Several breast diseases can increase the chances of having breast cancer. Changes in the cells of the breasts can lead to atypical hyperplasia. This condition can cause a three to fourfold increase in the possibility of getting breast cancer in the later years. This risk also exists if the atypical hyperplasia has occurred in other women of the family. Another such condition is the benign breast tumor condition known as fibro adenoma. However, women with fibrocystic breasts generally do not have any added vulnerability to breast cancer. Yet, such conditions could make the breasts lumpy and hide the real tumors (if any) during mammography.
(4) Lifestyle
In today’s world, lifestyle is the single largest contributing factor for the proliferation of breast cancer among women. Several elements of the lifestyle have been found to be directly accordant with the prevalence of breast cancer. Smoking and alcoholism in women are among the chief factors. Even diet has been pointed out as an important risk factor. Women who consume a diet with more high-cholesterol fats in them have higher chances of breast cancer. At the same time leading a sedentary lifestyle without indulging much in physical activity are also potentially dangerous.
(5) Radiation
It has been found that women who undergo radiation therapies in their chest region at a young age have an increased risk of developing breast cancer in their later lives. Radiation therapy is generally prescribed for women with conditions like Hodgkin’s disease or non-Hodgkin’s lymphoma. So women who have undergone such treatments may get breast cancer in their later years.
(6) Hormonal Imbalances There are several factors that can change the hormone balance of the body. Some of them are:- a) Beginning the menstrual cycle early, i.e. before the age of twelve years, b) Having the first pregnancy after the age of thirty years, c) Having no pregnancy at all, d) Having a late menopause. All these conditions can increase the level of estrogen in the body. This increases the risk of getting breast cancer to a mild extent. Apart from that women who take regular birth control pills, breast enhancement supplements, antidepressants and antihistamines and hormone modifying supplements stand at a higher risk to get breast cancers.
The above are the major risk factors for breast cancers. But since the study on breast cancers is not yet complete, the above is by no means a complete list. There are several other indications of breast cancers, like breast implant operations; but these have not yet been confirmed. The implants used in the earlier days were made of silicone gels. These were riskier in terms of breast cancer. However, nowadays the silicone gel implants have been replaced by saline implants. This has reduced the risk to a great extent.
It must be also noted that women have much higher chances of getting breast cancer than men. In fact, most people think that breast cancer is a disease that affects only women. This is not true. Men also get breast cancers, but to a much lesser degree than women. Also, age is a very important factor. The chances of getting breast cancer are much higher when the woman has crossed the age of 50 years.
Read more about the Breast Cancer Information and other breast care issues at http://www.mysecrethealth.com
Article Source: http://www.articlesbase.com/women's-issues-articles/what-are-the-risk-factors-for-breast-cancer-101136.html
Carcinogenesis and Cancer
Carcinogenesis is the creation of a cancer.
Cancer is, ultimately, a disease of genes. Typically, a series of several mutations is required before a cell becomes a cancer cell. We distinguish between oncogenes, which promote cancer when "switched on" by a mutation, and tumor suppressor genes, which prevent cancer unless "switched off" by a mutation. These mutations can have various causes: radiation or chemicals called carcinogens; some inherited predisposition is not uncommon; some viruses that can cause cancer have also been described. Usually, they carry in their genome some oncogene or tumor suppressor inactivating gene. In about 15% of all cancers, viruses seem to play a role. Finally, damage by free radicals, which are a natural by-product of oxygen metabolism, can cause mutations in the DNA.
For most of the cancers, it cannot be told which event was the initial cause. However, with molecular biology, it is possible to characterize the mutations within a tumor, and to a certain extent to predict its behavior. For example, about half of the tumors are deficient in the tumor suppressor gene p53, also known as "the guardian of the genome". This is associated with poor prospects for the patient, since those tumor cells are unlikely to go into apoptosis (programmed cell death) after they are damaged by therapy. There are more mutations that make a tumor more malignant. Telomerase mutations enable a tumor cell to divide indefinitely. Other mutations enable the tumor to grow new blood vessels to feed it, or to detach from the surrounding tissue, spreading to other parts of the body.
Malignant tumors such as carcinoma or sarcoma, lymphoma or leukemia originate from a cell or a group of cells in a multicellular organism that have several distinct properties:
increased cell division rate
not controllable by growth factors anymore
altered differentiation (specialization) ability
no ability for contact inhibition
ability to invade neighbouring tissue
ability to build metastases
ability to promote blood vessel growth
A cell that degenerates into a tumor cell does usually not acquire all these properties at once, but its daughter cells are selected to build them. This process is called cellular evolution. A first step in the development of a tumor cell is usually a small change in the DNA, often a point mutation, which leads, among other things, to a genetic instability of the cell. The instability increases to a point where the cell loses whole chromosomes, or has double ones. Also, the DNA methylation pattern of the cell changes, activating and deactivating genes more or less at random. Cells that divide at a high rate, such as stem cells, show a higher risk of becoming tumor cells than those which divide less or not at all, for example, neurons. If the initial tumor cell (or group of tumor cells) is not removed by the immune system, it will develop into cancer.
In cellular model systems, cells are exposed to carcinogenic influences (chemicals, radiation). In these systems, the first signs of a cell developing into a tumor cell are :
Immortality. The usual number of cell divisions for a mammalian cell is 50-60 (cell senescence), then it ceases to divide. Tumor cells keep dividing forever.
Altered morphology.
Building of cellular clusters (Foci).
Loss of contact inhibition.
Low or no need for growth factors.
Metastasis
Cancers are capable of spreading through the body by two mechanisms: local invasion and distant metastasis. Invasion refers to the direct migration and penetration by cancer cells into neighboring tissues. Metastasis refers to the ability of cancer cells to penetrate into lymphatic and blood vessels, circulate through the bloodstream, and then invade normal tissues elsewhere in the body. Cancer is most deadly when it metastasizes.
Forms of cancer
The term cancer is very broad and covers many different illnesses including:
Bladder cancer
Bone cancer
Brain tumor
Breast cancer
Cervical cancer
Colorectal cancer (includes colon, rectum, anus, and appendix)
Cancer of the esophagus
Hodgkin's disease
Kidney cancer
Cancer of the larynx
Leukemia
Liver cancer
Lung cancer
Lymphoma
Melanoma
Moles and dysplastic nevi
Multiple myeloma
Muscular Cancer
Non-Hodgkin's lymphoma
Oral cancer
Ovarian cancer
Cancer of the pancreas
Prostate cancer
Skin cancer
Stomach cancer
Testicular cancer
Teratoma
Thyroid cancer
Cancer of the uterus
Clinical aspects
The field of medicine concerned with the treatment of cancer is oncology.
Cancer has become an important problem with the rise in life expectancy, as the above mentioned mutations become more likely the longer a person lives. Though great progress in treatment has been made, most cancers in advanced stages remain incurable and ultimately fatal.
Treatment of cancer typically involves surgery to remove tumors and nearby lymph nodes to which the cancer may have spread, combined with radiation therapy and/or chemotherapy. The latter two target cells in the body that are rapidly dividing. This includes the cancer cells but also certain healthy ones, which is the reason for the severe side effects of these treatments.
Article Source: http://www.articlesbase.com/diseases-and-conditions-articles/carcinogenesis-and-cancer-149674.html
Cancer is, ultimately, a disease of genes. Typically, a series of several mutations is required before a cell becomes a cancer cell. We distinguish between oncogenes, which promote cancer when "switched on" by a mutation, and tumor suppressor genes, which prevent cancer unless "switched off" by a mutation. These mutations can have various causes: radiation or chemicals called carcinogens; some inherited predisposition is not uncommon; some viruses that can cause cancer have also been described. Usually, they carry in their genome some oncogene or tumor suppressor inactivating gene. In about 15% of all cancers, viruses seem to play a role. Finally, damage by free radicals, which are a natural by-product of oxygen metabolism, can cause mutations in the DNA.
For most of the cancers, it cannot be told which event was the initial cause. However, with molecular biology, it is possible to characterize the mutations within a tumor, and to a certain extent to predict its behavior. For example, about half of the tumors are deficient in the tumor suppressor gene p53, also known as "the guardian of the genome". This is associated with poor prospects for the patient, since those tumor cells are unlikely to go into apoptosis (programmed cell death) after they are damaged by therapy. There are more mutations that make a tumor more malignant. Telomerase mutations enable a tumor cell to divide indefinitely. Other mutations enable the tumor to grow new blood vessels to feed it, or to detach from the surrounding tissue, spreading to other parts of the body.
Malignant tumors such as carcinoma or sarcoma, lymphoma or leukemia originate from a cell or a group of cells in a multicellular organism that have several distinct properties:
increased cell division rate
not controllable by growth factors anymore
altered differentiation (specialization) ability
no ability for contact inhibition
ability to invade neighbouring tissue
ability to build metastases
ability to promote blood vessel growth
A cell that degenerates into a tumor cell does usually not acquire all these properties at once, but its daughter cells are selected to build them. This process is called cellular evolution. A first step in the development of a tumor cell is usually a small change in the DNA, often a point mutation, which leads, among other things, to a genetic instability of the cell. The instability increases to a point where the cell loses whole chromosomes, or has double ones. Also, the DNA methylation pattern of the cell changes, activating and deactivating genes more or less at random. Cells that divide at a high rate, such as stem cells, show a higher risk of becoming tumor cells than those which divide less or not at all, for example, neurons. If the initial tumor cell (or group of tumor cells) is not removed by the immune system, it will develop into cancer.
In cellular model systems, cells are exposed to carcinogenic influences (chemicals, radiation). In these systems, the first signs of a cell developing into a tumor cell are :
Immortality. The usual number of cell divisions for a mammalian cell is 50-60 (cell senescence), then it ceases to divide. Tumor cells keep dividing forever.
Altered morphology.
Building of cellular clusters (Foci).
Loss of contact inhibition.
Low or no need for growth factors.
Metastasis
Cancers are capable of spreading through the body by two mechanisms: local invasion and distant metastasis. Invasion refers to the direct migration and penetration by cancer cells into neighboring tissues. Metastasis refers to the ability of cancer cells to penetrate into lymphatic and blood vessels, circulate through the bloodstream, and then invade normal tissues elsewhere in the body. Cancer is most deadly when it metastasizes.
Forms of cancer
The term cancer is very broad and covers many different illnesses including:
Bladder cancer
Bone cancer
Brain tumor
Breast cancer
Cervical cancer
Colorectal cancer (includes colon, rectum, anus, and appendix)
Cancer of the esophagus
Hodgkin's disease
Kidney cancer
Cancer of the larynx
Leukemia
Liver cancer
Lung cancer
Lymphoma
Melanoma
Moles and dysplastic nevi
Multiple myeloma
Muscular Cancer
Non-Hodgkin's lymphoma
Oral cancer
Ovarian cancer
Cancer of the pancreas
Prostate cancer
Skin cancer
Stomach cancer
Testicular cancer
Teratoma
Thyroid cancer
Cancer of the uterus
Clinical aspects
The field of medicine concerned with the treatment of cancer is oncology.
Cancer has become an important problem with the rise in life expectancy, as the above mentioned mutations become more likely the longer a person lives. Though great progress in treatment has been made, most cancers in advanced stages remain incurable and ultimately fatal.
Treatment of cancer typically involves surgery to remove tumors and nearby lymph nodes to which the cancer may have spread, combined with radiation therapy and/or chemotherapy. The latter two target cells in the body that are rapidly dividing. This includes the cancer cells but also certain healthy ones, which is the reason for the severe side effects of these treatments.
Article Source: http://www.articlesbase.com/diseases-and-conditions-articles/carcinogenesis-and-cancer-149674.html
Liver Cancer - Causes, Symptoms and Treatment
The liver is the largest internal organ in the body. It is also known as primary liver cancer or hepatoma and hepatocellular carcinoma is a cancer arising from the liver.The liver performs several vital functions. It processes and stores many of the nutrients absorbed from the intestine. It also makes some of the clotting factors needed to stop bleeding from a cut or injury. Hemangioma (he-man-ge-O-muh) is the most common type of benign liver tumor. It starts in blood vessels and Hepatic adenomas are benign tumors that start from the main type of liver cells (hepatocytes). Women have a much higher chance of having one of these tumors if they take birth control pills, although this is rare. Stopping the pills can cause the tumor to shrink. Hepatic adenomascancer begins in many spots throughout the liver and is not confined to a single tumor. This is most often seen in people with liver cirrhosis and is the most common pattern seen in the United States.
Hepatic tumors also called Liver cancer. Hepatic tumors is are tumors or growths on or in the liver. There are many forms of liver tumors premary is Malignant. Malignant, primary liver cancer is hepatocellular carcinoma (also named hepatoma, which is a misnomer). These growths can be benign or malignant (cancerous). They may be discovered on medical imaging (even for a different reason than the cancer itself). Most of the time when cancer is found in the liver, it did not start there but spread to the liver from a cancer that began somewhere else in the body. These tumors are named after the place where they began (primary site) and are further described as metastatic. Symptoms can include a lump or pain on the right side of your abdomen and yellowing of the skin. However, you may not have symptoms and the cancer may not be found until it is advanced.
Some researchers believe that cancer starts with damage to DNA the material that contains the instructions for every chemical process in your body, including the rate of cellular growth. DNA damage causes changes in these instructions. Liver cancer also occurs as metastatic cancer, which happens when tumors from other parts of the body spread (metastasize) to the liver. In the liver cancer some cells begin to grow abnormally. One result is that cells may begin to grow out of control and eventually form a tumor a mass of malignant cells. In the United States, most cancer found in the liver spread there after originating elsewhere. Rather than being called liver cancer, this type of cancer in the liver is named after the organ in which it began such as metastatic colon cancer in cancer that starts in the colon and spreads to the liver.
Causes of liver Cancer
Hepatitis B virus (HBV) infection is the main causes of liver cancer. Liver cancer relates to (correlates with) the frequency of chronic hepatitis B virus infection. Studies in animals also have provided that hepatitis B virus can cause liver cancer. For example, liver cancer develops in other mammals that are naturally infected with hepatitis B virus-related viruses. Finally, by infecting transgenic mice with certain parts of the hepatitis B virus, scientists caused liver cancer to develop in mice that do not usually develop liver cancer.
Symptoms of liver cancer
Liver cancer is very common larges countries in world wide. Generally is discovered at a very advanced stage of cancer disease for several reasons. In addition, patients from these regions actually have more aggressive liver cancer disease. live cancer tumor usually reaches an advanced stage and causes symptoms more rapidly. Abdominal pain is the most common symptom of liver cancer and usually signifies a very large tumor or widespread involvement of the liver and other symptom is weight loss. These symptoms are less common in individuals with liver cancer in the U.S.an additionally symptoms is ascites (abdominal fluid and swelling), jaundice (yellow color of the skin), or muscle wasting.
Treatment of liver cancer
The treatment of liver cancer is overall condition of the patient. First treatment if liver cancer is Chemotherapy. Chemotherapy is a powerful drugs to kill cancer cells. Chemotherapy is anot effective not some cases of liver cancer but type of chemotherapy is known as chemoembolization is an important part of treatment for HCC. chemoembolization causes many of the same side effects as other forms of chemotherapy, including abdominal pain, nausea and vomiting. Second treatment is surgery. Surgery is best treatment for localized resectable cancer is usually an operation known as surgical resection. In some cases, the area of the liver where the cancer is found can be completely removed. Alcohol injection has been shown to improve survival in people with small hepatocellular tumors. It may also be used to help reduce symptoms in cases of metastatic liver cancer. The most common side effect is leaking of alcohol onto the liver or into the abdominal cavity.
Article Source: http://www.articlesbase.com/diseases-and-conditions-articles/liver-cancer-causes-symptoms-and-treatment-152364.html
Hepatic tumors also called Liver cancer. Hepatic tumors is are tumors or growths on or in the liver. There are many forms of liver tumors premary is Malignant. Malignant, primary liver cancer is hepatocellular carcinoma (also named hepatoma, which is a misnomer). These growths can be benign or malignant (cancerous). They may be discovered on medical imaging (even for a different reason than the cancer itself). Most of the time when cancer is found in the liver, it did not start there but spread to the liver from a cancer that began somewhere else in the body. These tumors are named after the place where they began (primary site) and are further described as metastatic. Symptoms can include a lump or pain on the right side of your abdomen and yellowing of the skin. However, you may not have symptoms and the cancer may not be found until it is advanced.
Some researchers believe that cancer starts with damage to DNA the material that contains the instructions for every chemical process in your body, including the rate of cellular growth. DNA damage causes changes in these instructions. Liver cancer also occurs as metastatic cancer, which happens when tumors from other parts of the body spread (metastasize) to the liver. In the liver cancer some cells begin to grow abnormally. One result is that cells may begin to grow out of control and eventually form a tumor a mass of malignant cells. In the United States, most cancer found in the liver spread there after originating elsewhere. Rather than being called liver cancer, this type of cancer in the liver is named after the organ in which it began such as metastatic colon cancer in cancer that starts in the colon and spreads to the liver.
Causes of liver Cancer
Hepatitis B virus (HBV) infection is the main causes of liver cancer. Liver cancer relates to (correlates with) the frequency of chronic hepatitis B virus infection. Studies in animals also have provided that hepatitis B virus can cause liver cancer. For example, liver cancer develops in other mammals that are naturally infected with hepatitis B virus-related viruses. Finally, by infecting transgenic mice with certain parts of the hepatitis B virus, scientists caused liver cancer to develop in mice that do not usually develop liver cancer.
Symptoms of liver cancer
Liver cancer is very common larges countries in world wide. Generally is discovered at a very advanced stage of cancer disease for several reasons. In addition, patients from these regions actually have more aggressive liver cancer disease. live cancer tumor usually reaches an advanced stage and causes symptoms more rapidly. Abdominal pain is the most common symptom of liver cancer and usually signifies a very large tumor or widespread involvement of the liver and other symptom is weight loss. These symptoms are less common in individuals with liver cancer in the U.S.an additionally symptoms is ascites (abdominal fluid and swelling), jaundice (yellow color of the skin), or muscle wasting.
Treatment of liver cancer
The treatment of liver cancer is overall condition of the patient. First treatment if liver cancer is Chemotherapy. Chemotherapy is a powerful drugs to kill cancer cells. Chemotherapy is anot effective not some cases of liver cancer but type of chemotherapy is known as chemoembolization is an important part of treatment for HCC. chemoembolization causes many of the same side effects as other forms of chemotherapy, including abdominal pain, nausea and vomiting. Second treatment is surgery. Surgery is best treatment for localized resectable cancer is usually an operation known as surgical resection. In some cases, the area of the liver where the cancer is found can be completely removed. Alcohol injection has been shown to improve survival in people with small hepatocellular tumors. It may also be used to help reduce symptoms in cases of metastatic liver cancer. The most common side effect is leaking of alcohol onto the liver or into the abdominal cavity.
Article Source: http://www.articlesbase.com/diseases-and-conditions-articles/liver-cancer-causes-symptoms-and-treatment-152364.html
Detect your Cervical Cancer With Pap Test!
Cervical cancer
is the cancer of the cervix. It is a disease caused by the abnormal growth and division of cells that forms in the lining of the cervix. It is the second common form of cancer that affects women today. It is very common in middle age women and older.
The statistics of cervical cancer in the United States, according to American Cancer Society (ACS), shows that about 11,150 women are diagnosing with this cancer and approximately 3,670 women die from this cancer every year.
To understand more about cervical cancer, it is important to note what a cervix is first. The cervix is the lower part of the uterus (womb) that connects the uterus to the vagina (birth canal) in a woman's body.
Usually, cervical cancer exhibits no symptoms to detect the presence of cancer in your body. It is known as a slow growing form of cancer. When cancer develops in your body, the healthy cells in the cervix begin to change into abnormal cells, which then turn into pre-cancerous cells. If left untreated, these pre-cancerous cells will turn into cancer.
Risk factors of cervical cancer:
Although the cause of cervical cancer is not known there are certain risk factors that increase the risk of developing this cancer. Risk factors are the things that will affect the chances of developing a disease greater.
Human Papilloma Virus
(HPV), a sexual transmitted disease is highly associated with invasive cervical cancer.
Sexual transmitted diseases occur due to sexual contacts with an infected person. Chlamydia, syphilis, gonorrhea, genital herpes, HIV/AIDS are some of he examples of sexual transmitted diseases.
Other risk factors that increase your chances of developing cervical cancer are: a history of sexual transmitted diseases, having sexual intercourse with multiple partners, having sexual activities in very young age (without using contraceptives).
Smoking doubles your risk of having cancer of the cervix. Weakened immune system, regular usage of birth control pills, age, giving birth to many children, and irregular pap tests increases your risk of developing cervical cancer.
As the cause of cervical cancer is unknown, it can be detected with regular Pap tests or pap smears. It is very important for you to have regular Pap tests to identify the condition early to take appropriate treatment and prevent cervical cancer from developing.
Pap test to detect cervical cancer:
With Pap tests, you can detect the cancer in the early stages before it spreads to other parts of the body. Pap smear is a procedure where scraped cells from the cervix are examined under a microscope to check for the changes in the cells of your cervix that leads to cervical cancer.
The rate of cervical cancer in women has greatly decreased in recent years in the United States due to regular pap smears.
As cervical cancer is a malignant tumor, it is very important for you to have Pap tests done annually. Remember, it is not a good idea to wait for signs to consult a doctor as early detection is the key to being treated successfully. Visit Online Cancer Blog
Article Source: http://www.articlesbase.com/cancer-articles/detect-your-cervical-cancer-with-pap-test-297160.html
is the cancer of the cervix. It is a disease caused by the abnormal growth and division of cells that forms in the lining of the cervix. It is the second common form of cancer that affects women today. It is very common in middle age women and older.
The statistics of cervical cancer in the United States, according to American Cancer Society (ACS), shows that about 11,150 women are diagnosing with this cancer and approximately 3,670 women die from this cancer every year.
To understand more about cervical cancer, it is important to note what a cervix is first. The cervix is the lower part of the uterus (womb) that connects the uterus to the vagina (birth canal) in a woman's body.
Usually, cervical cancer exhibits no symptoms to detect the presence of cancer in your body. It is known as a slow growing form of cancer. When cancer develops in your body, the healthy cells in the cervix begin to change into abnormal cells, which then turn into pre-cancerous cells. If left untreated, these pre-cancerous cells will turn into cancer.
Risk factors of cervical cancer:
Although the cause of cervical cancer is not known there are certain risk factors that increase the risk of developing this cancer. Risk factors are the things that will affect the chances of developing a disease greater.
Human Papilloma Virus
(HPV), a sexual transmitted disease is highly associated with invasive cervical cancer.
Sexual transmitted diseases occur due to sexual contacts with an infected person. Chlamydia, syphilis, gonorrhea, genital herpes, HIV/AIDS are some of he examples of sexual transmitted diseases.
Other risk factors that increase your chances of developing cervical cancer are: a history of sexual transmitted diseases, having sexual intercourse with multiple partners, having sexual activities in very young age (without using contraceptives).
Smoking doubles your risk of having cancer of the cervix. Weakened immune system, regular usage of birth control pills, age, giving birth to many children, and irregular pap tests increases your risk of developing cervical cancer.
As the cause of cervical cancer is unknown, it can be detected with regular Pap tests or pap smears. It is very important for you to have regular Pap tests to identify the condition early to take appropriate treatment and prevent cervical cancer from developing.
Pap test to detect cervical cancer:
With Pap tests, you can detect the cancer in the early stages before it spreads to other parts of the body. Pap smear is a procedure where scraped cells from the cervix are examined under a microscope to check for the changes in the cells of your cervix that leads to cervical cancer.
The rate of cervical cancer in women has greatly decreased in recent years in the United States due to regular pap smears.
As cervical cancer is a malignant tumor, it is very important for you to have Pap tests done annually. Remember, it is not a good idea to wait for signs to consult a doctor as early detection is the key to being treated successfully. Visit Online Cancer Blog
Article Source: http://www.articlesbase.com/cancer-articles/detect-your-cervical-cancer-with-pap-test-297160.html
Bone Cancer – Information on Bone Cancer
Bone cancer that originates in the bone — primary bone cancer — is rare. Fewer than 2,500 Americans are diagnosed with this type of cancer each year. The condition affects more children than adults. Bone cancer is a malignant (cancerous) tumor of the bone that destroys normal bone tissue (1). Not all bone tumors are malignant. In fact, benign (noncancerous) bone tumors are more common than malignant ones. Both malignant and benign bone tumors may grow and compress healthy bone tissue, but benign tumors do not spread, do not destroy bone tissue, and are rarely a threat to life.
Most of the time when someone with cancer is told they have bone cancer, the doctor is talking about a cancer that spread there from somewhere else. This is called metastatic cancer and can be seen in people with advanced breast cancer, prostate cancer, lung cancer as well as many others. When these cancers in the bone are examined under a microscope they resemble the tissue they came from. If someone has lung cancer spread to bone, the cells of the cancer look and act like lung cancer cells, not bone cancer cells, even after they have spread from the lungs to the bones. They are treated with the same kind of treatment (chemotherapy drugs, for example) that is used for lung cancer.
Malignant tumors that begin in bone tissue are called primary bone cancer. Cancer that metastasizes (spreads) to the bones from other parts of the body, such as the breast, lung, or prostate, is called metastatic cancer, and is named for the organ or tissue in which it began. Primary bone cancer is far less common than cancer that spreads to the bones.
Bone cancer: Primary bone cancer is cancer that forms in cells of the bone. Some types of primary bone cancer are osteosarcoma, Ewing's sarcoma, malignant fibrous histiocytoma, and chondrosarcoma. Secondary bone cancer is cancer that spreads to the bone from another part of the body (such as the prostate, breast, or lung). The most common types of primary bone tumour are osteosarcoma and Ewing's sarcoma, both of which are most frequently diagnosed in children and young adults.
The first symptom of bone cancer is usually pain or tenderness near the cancer. Bone pain is caused by stretching of the periosteum (thick membrane that covers bone) by the cancer, or by stimulation of nerves within the bone. Bone pain may be hard to differentiate from ordinary low back pain or arthritis. Usually the pain due to bone metastasis is fairly constant, even at night. It can be worse in different positions, such as standing up, which may compress the cancer in a weight bearing bone. If pain lasts for more than a week or two, doesn't seem to be going away, and is unlike other pain that may have been experienced, it should be evaluated by a physician.
Bone cancer is caused by a problem with the cells that make bone. More than 2,000 people are diagnosed in the United States each year with a bone tumor. Bone tumors occur most commonly in children and adolescents and are less common in older adults. Cancer involving the bone in older adults is most commonly the result of metastatic spread from another tumor.
The most common symptom of bone cancer is pain. Other symptoms may vary depending on the location and size of the cancer. Surgery is often the main treatment for bone cancer. Other treatments may include amputation, chemotherapy and radiation.
Article Source: http://www.articlesbase.com/health-articles/bone-cancer-information-on-bone-cancer-395971.html
Most of the time when someone with cancer is told they have bone cancer, the doctor is talking about a cancer that spread there from somewhere else. This is called metastatic cancer and can be seen in people with advanced breast cancer, prostate cancer, lung cancer as well as many others. When these cancers in the bone are examined under a microscope they resemble the tissue they came from. If someone has lung cancer spread to bone, the cells of the cancer look and act like lung cancer cells, not bone cancer cells, even after they have spread from the lungs to the bones. They are treated with the same kind of treatment (chemotherapy drugs, for example) that is used for lung cancer.
Malignant tumors that begin in bone tissue are called primary bone cancer. Cancer that metastasizes (spreads) to the bones from other parts of the body, such as the breast, lung, or prostate, is called metastatic cancer, and is named for the organ or tissue in which it began. Primary bone cancer is far less common than cancer that spreads to the bones.
Bone cancer: Primary bone cancer is cancer that forms in cells of the bone. Some types of primary bone cancer are osteosarcoma, Ewing's sarcoma, malignant fibrous histiocytoma, and chondrosarcoma. Secondary bone cancer is cancer that spreads to the bone from another part of the body (such as the prostate, breast, or lung). The most common types of primary bone tumour are osteosarcoma and Ewing's sarcoma, both of which are most frequently diagnosed in children and young adults.
The first symptom of bone cancer is usually pain or tenderness near the cancer. Bone pain is caused by stretching of the periosteum (thick membrane that covers bone) by the cancer, or by stimulation of nerves within the bone. Bone pain may be hard to differentiate from ordinary low back pain or arthritis. Usually the pain due to bone metastasis is fairly constant, even at night. It can be worse in different positions, such as standing up, which may compress the cancer in a weight bearing bone. If pain lasts for more than a week or two, doesn't seem to be going away, and is unlike other pain that may have been experienced, it should be evaluated by a physician.
Bone cancer is caused by a problem with the cells that make bone. More than 2,000 people are diagnosed in the United States each year with a bone tumor. Bone tumors occur most commonly in children and adolescents and are less common in older adults. Cancer involving the bone in older adults is most commonly the result of metastatic spread from another tumor.
The most common symptom of bone cancer is pain. Other symptoms may vary depending on the location and size of the cancer. Surgery is often the main treatment for bone cancer. Other treatments may include amputation, chemotherapy and radiation.
Article Source: http://www.articlesbase.com/health-articles/bone-cancer-information-on-bone-cancer-395971.html
Breast Cancer Symptoms
Breast cancer symptoms can be experienced by men as well as women but breast cancer is very rare in men compared to women. More than 1 in 10 women are likely to suffer from breast cancer symptoms, and be diagnosed with breast cancer, in a lifetime. Breast cancer symptoms can be detected when a lump, tumor, or cyst grows large enough to either be felt or seen on a mammogram. Sometimes a tumor isn’t found for many years. Breast cancer symptoms don’t often manifest themselves until the cancer is already in its later stages of growth, and may have already metastasized to other more vital areas of the body. That is why it is so important for women to regularly get checked.
Breast cancer symptoms are often subtle, and self discovery can be elusive. Due to the high incidence of breast cancer among older women, screening is now recommended in many countries.
Lumps or masses in the breast are not unusual, and most of them are not cancerous. Some breast masses can be felt during a breast exam.
Lump may form in the breast, chest or under the arm if the cancer is in the breast or near the chest wall. You will also notice a change in the size, shape and skin of the breast.
Earlier the diagnosis of breast cancer always involved the removal of the breast and the surrounding skin, muscles underneath the breast and the lymph nodes underneath the arm. Today’s method of diagnosis is well advanced without the above mentioned procedure radical mastectomy.
Among young women, a lump that moves may be a sign of fibrocystic breast disease. But simply asking questions is not enough; a combination of tests is used to make a final diagnosis.
Generally, breast cancer is a much more aggressive disease in younger women. Generally a lump that is cancerous will not be tender to the touch, it will be hard, non-movable, and not change rapidly in size (within several days or weeks). If a lump is tender, it could be a cyst or a swollen lymph node. Genetic counseling and genetic testing should be considered for families who may carry a heritidary form of cancer.
Inflammatory breast cancer is an uncommon type of breast cancer, which includes the breast being warm, red, and swollen.The inflammation occurs because the cancer cells block the lymphatic vessels in the skin of the breast . It doesn’t always involve a lump.
Breast cancer is a common disease. Each year, approximately 200,000 women in the United States are diagnosed with breast cancer, and one in nine American women will develop breast cancer in her lifetime. Breast cancer occurs much more commonly in women and fewer than 1 in 100 of breast cancers occur in men. In the UK, approximately 250 men are diagnosed with breast cancer each year. Breast cancer starts in the cells of the breast. The breast tissue covers an area larger than just the breast.
Women with one of these defects have up to an 80% chance of getting breast cancer sometime during their life. Women who attend Infinite Boundaries retreats are in all stages of breast cancer. Some are newly diagnosed while others may have been treated for breast cancer years ago. Women who drink alcohol have a modestly increased risk. The more you drink, the greater your risk
Women had limited knowledge of their relative risk of developing breast cancer, of associated risk factors and of the diversity of potential breast cancer-related symptoms. Older women were particularly poor at identifying symptoms of breast cancer, risk factors associated with breast cancer and their personal risk of developing the disease. Women, sometimes, have lumps in their breasts which have been there for a lifetime. They’re usually harmless fibroids, and never conclusively mean you’ve developed breast cancer. Women are very conscious about their breast care. Beautiful and healthy breast are one of the most cherished dream of women.
Article Source: http://www.articlesbase.com/health-articles/breast-cancer-symptoms-417710.html
Breast cancer symptoms are often subtle, and self discovery can be elusive. Due to the high incidence of breast cancer among older women, screening is now recommended in many countries.
Lumps or masses in the breast are not unusual, and most of them are not cancerous. Some breast masses can be felt during a breast exam.
Lump may form in the breast, chest or under the arm if the cancer is in the breast or near the chest wall. You will also notice a change in the size, shape and skin of the breast.
Earlier the diagnosis of breast cancer always involved the removal of the breast and the surrounding skin, muscles underneath the breast and the lymph nodes underneath the arm. Today’s method of diagnosis is well advanced without the above mentioned procedure radical mastectomy.
Among young women, a lump that moves may be a sign of fibrocystic breast disease. But simply asking questions is not enough; a combination of tests is used to make a final diagnosis.
Generally, breast cancer is a much more aggressive disease in younger women. Generally a lump that is cancerous will not be tender to the touch, it will be hard, non-movable, and not change rapidly in size (within several days or weeks). If a lump is tender, it could be a cyst or a swollen lymph node. Genetic counseling and genetic testing should be considered for families who may carry a heritidary form of cancer.
Inflammatory breast cancer is an uncommon type of breast cancer, which includes the breast being warm, red, and swollen.The inflammation occurs because the cancer cells block the lymphatic vessels in the skin of the breast . It doesn’t always involve a lump.
Breast cancer is a common disease. Each year, approximately 200,000 women in the United States are diagnosed with breast cancer, and one in nine American women will develop breast cancer in her lifetime. Breast cancer occurs much more commonly in women and fewer than 1 in 100 of breast cancers occur in men. In the UK, approximately 250 men are diagnosed with breast cancer each year. Breast cancer starts in the cells of the breast. The breast tissue covers an area larger than just the breast.
Women with one of these defects have up to an 80% chance of getting breast cancer sometime during their life. Women who attend Infinite Boundaries retreats are in all stages of breast cancer. Some are newly diagnosed while others may have been treated for breast cancer years ago. Women who drink alcohol have a modestly increased risk. The more you drink, the greater your risk
Women had limited knowledge of their relative risk of developing breast cancer, of associated risk factors and of the diversity of potential breast cancer-related symptoms. Older women were particularly poor at identifying symptoms of breast cancer, risk factors associated with breast cancer and their personal risk of developing the disease. Women, sometimes, have lumps in their breasts which have been there for a lifetime. They’re usually harmless fibroids, and never conclusively mean you’ve developed breast cancer. Women are very conscious about their breast care. Beautiful and healthy breast are one of the most cherished dream of women.
Article Source: http://www.articlesbase.com/health-articles/breast-cancer-symptoms-417710.html
What Is Lung Cancer And What Cause It
Lung cancer is the leading cause of cancer deaths in both women and men in the United States and throughout the world. Lung cancer has surpassed breast cancer as the leading cause of cancer deaths in women.
In the United States in 2007, 160,390 people were projected to die from lung cancer, which is more than the number of deaths from colorectal, breast, and prostate cancer combined.
Only about 2% of those diagnosed with lung cancer that has spread to other areas of the body are alive five years after the diagnosis, although the survival rates for lung cancers diagnosed at a very early stage are higher, with approximately 49% surviving for five years or longer.
Some lung tumors are metastatic from cancers elsewhere in the body. The lungs are a common site for metastasis. If this is the case, the cancer is not considered to be lung cancer. For example, if prostate cancer spreads via the bloodstream to the lungs, it is metastatic prostate cancer (a secondary cancer) in the lung and is not called lung cancer.
Cancer occurs when normal cells undergo a transformation that causes them to grow and multiply without the normal controls. The cells form a mass or tumor that differs from the surrounding tissues from which it arises. Tumors are dangerous because they take oxygen, nutrients, and space from healthy cells.
About 90% of lung cancers arise due to tobacco use. Cigarette smoking is the most important cause of lung cancer. Research as far back as the 1950s clearly established this relationship. Cigarette smoke contains more than 4,000 chemicals, many of which have been identified as causing cancer. A person who smokes more than one pack of cigarettes per day has a risk of developing lung cancer 20-25 times greater than someone who has never smoked.
However, Once a person quits smoking, his or her risk for lung cancer gradually decreases. About 15 years after quitting, the risk for lung cancer decreases to the level of someone who never smoked. Cigar and pipe smoking also increases the risk of lung cancer but not as much as smoking cigarettes.
Most lung tumors are malignant. This means that they invade and destroy the healthy tissues around them and can spread throughout the body.
The tumors can also spread to nearby lymph nodes or through the bloodstream to other organs. This process is called metastasis. When lung cancer metastasizes, the tumor in the lung is called the primary tumor, and the tumors in other parts of the body are called secondary tumors or metastatic tumors.
Adenocarcinoma (an NSCLC) is the most common type of lung cancer, making up 30%-40% of all cases. A subtype of adenocarcinoma is called bronchoalveolar cell carcinoma, which creates a pneumonia-like appearance on chest x-rays. Squamous cell carcinoma (an NSCLC) is the second most common type of lung cancer, making up about 30% of all lung cancers. Large cell cancer (another NSCLC) makes up 10% of all cases. SCLC makes up 20% of all cases. And finally, Carcinoid tumors account for only 1% of all cases.
Lung cancers are usually divided into two main groups that account for about 95% of all cases. These division into groups is based on the type of cells that make up the cancer. About 5% of lung cancers are of rare cell types, including carcinoid tumor, lymphoma, and others.
The two main types of lung cancer are characterized by the cell size of the tumor when viewed under the microscope. They are called small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). NSCLC includes several subtypes of tumors. SCLCs are less common, but they grow more quickly and are more likely to metastasize than NSCLCs. Often, SCLCs have already spread to other parts of the body when the cancer is diagnosed.
Up to one-fourth of all people with lung cancer may have no symptoms when the cancer is diagnosed. These cancers usually are identified incidentally when a chest x-ray is performed for another reason. The majority of people, however, develop symptoms. The symptoms are due to direct effects of the primary tumor, to effects of metastatic tumors in other parts of the body, or to disturbances of hormones, blood, or other systems caused by the cancer.
Symptoms of primary lung cancers include cough, coughing up blood, chest pain, and shortness of breath. Symptoms of metastatic lung tumors depend on the location and size. About 30%-40% of people with lung cancer have some symptoms or signs of metastatic disease.
A cough that does not go away or gets worse over time should be evaluated by a health-care provider. Also, Coughing up blood (hemoptysis) occurs in a significant number of people who have lung cancer. Any amount of coughed-up blood is cause for concern. Chest pain is a symptom in about one-fourth of people with lung cancer. The pain is dull, aching, and persistent and may involve other structures surrounding the lung.
Additionally, shortness of breath usually results from a blockage to the flow of air in part of the lung, collection of fluid around the lung (pleural effusion), or the spread of tumor throughout the lungs. Wheezing or hoarseness may signal blockage or inflammation in the lungs that may go along with cancer. Finally, Repeated respiratory infections, such as bronchitis or pneumonia, can be a sign of lung cancer.
Article Source: http://www.articlesbase.com/health-articles/what-is-lung-cancer-and-what-cause-it-422720.html
In the United States in 2007, 160,390 people were projected to die from lung cancer, which is more than the number of deaths from colorectal, breast, and prostate cancer combined.
Only about 2% of those diagnosed with lung cancer that has spread to other areas of the body are alive five years after the diagnosis, although the survival rates for lung cancers diagnosed at a very early stage are higher, with approximately 49% surviving for five years or longer.
Some lung tumors are metastatic from cancers elsewhere in the body. The lungs are a common site for metastasis. If this is the case, the cancer is not considered to be lung cancer. For example, if prostate cancer spreads via the bloodstream to the lungs, it is metastatic prostate cancer (a secondary cancer) in the lung and is not called lung cancer.
Cancer occurs when normal cells undergo a transformation that causes them to grow and multiply without the normal controls. The cells form a mass or tumor that differs from the surrounding tissues from which it arises. Tumors are dangerous because they take oxygen, nutrients, and space from healthy cells.
About 90% of lung cancers arise due to tobacco use. Cigarette smoking is the most important cause of lung cancer. Research as far back as the 1950s clearly established this relationship. Cigarette smoke contains more than 4,000 chemicals, many of which have been identified as causing cancer. A person who smokes more than one pack of cigarettes per day has a risk of developing lung cancer 20-25 times greater than someone who has never smoked.
However, Once a person quits smoking, his or her risk for lung cancer gradually decreases. About 15 years after quitting, the risk for lung cancer decreases to the level of someone who never smoked. Cigar and pipe smoking also increases the risk of lung cancer but not as much as smoking cigarettes.
Most lung tumors are malignant. This means that they invade and destroy the healthy tissues around them and can spread throughout the body.
The tumors can also spread to nearby lymph nodes or through the bloodstream to other organs. This process is called metastasis. When lung cancer metastasizes, the tumor in the lung is called the primary tumor, and the tumors in other parts of the body are called secondary tumors or metastatic tumors.
Adenocarcinoma (an NSCLC) is the most common type of lung cancer, making up 30%-40% of all cases. A subtype of adenocarcinoma is called bronchoalveolar cell carcinoma, which creates a pneumonia-like appearance on chest x-rays. Squamous cell carcinoma (an NSCLC) is the second most common type of lung cancer, making up about 30% of all lung cancers. Large cell cancer (another NSCLC) makes up 10% of all cases. SCLC makes up 20% of all cases. And finally, Carcinoid tumors account for only 1% of all cases.
Lung cancers are usually divided into two main groups that account for about 95% of all cases. These division into groups is based on the type of cells that make up the cancer. About 5% of lung cancers are of rare cell types, including carcinoid tumor, lymphoma, and others.
The two main types of lung cancer are characterized by the cell size of the tumor when viewed under the microscope. They are called small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). NSCLC includes several subtypes of tumors. SCLCs are less common, but they grow more quickly and are more likely to metastasize than NSCLCs. Often, SCLCs have already spread to other parts of the body when the cancer is diagnosed.
Up to one-fourth of all people with lung cancer may have no symptoms when the cancer is diagnosed. These cancers usually are identified incidentally when a chest x-ray is performed for another reason. The majority of people, however, develop symptoms. The symptoms are due to direct effects of the primary tumor, to effects of metastatic tumors in other parts of the body, or to disturbances of hormones, blood, or other systems caused by the cancer.
Symptoms of primary lung cancers include cough, coughing up blood, chest pain, and shortness of breath. Symptoms of metastatic lung tumors depend on the location and size. About 30%-40% of people with lung cancer have some symptoms or signs of metastatic disease.
A cough that does not go away or gets worse over time should be evaluated by a health-care provider. Also, Coughing up blood (hemoptysis) occurs in a significant number of people who have lung cancer. Any amount of coughed-up blood is cause for concern. Chest pain is a symptom in about one-fourth of people with lung cancer. The pain is dull, aching, and persistent and may involve other structures surrounding the lung.
Additionally, shortness of breath usually results from a blockage to the flow of air in part of the lung, collection of fluid around the lung (pleural effusion), or the spread of tumor throughout the lungs. Wheezing or hoarseness may signal blockage or inflammation in the lungs that may go along with cancer. Finally, Repeated respiratory infections, such as bronchitis or pneumonia, can be a sign of lung cancer.
Article Source: http://www.articlesbase.com/health-articles/what-is-lung-cancer-and-what-cause-it-422720.html
Risks of Colon Cancer in Women and Men
Cancer occurs when something goes wrong with this system, causing uncontrolled cell division and growth. Colon cancer is cancer of the large intestine (colon), the lower part of your digestive system. Most cases of colon cancer begin as small, noncancerous (benign) clumps of cells called adenomatous polyps. Rectal cancer is cancer of the last 6 inches of the colon. Together, they're often referred to as colorectal cancers.
Colorectal cancer is the second most common cancer killer overall and third most common cause of cancer-related death in the United States in both males and females. Who is at risk for colorectal cancer. Men tend to get colorectal cancer at an earlier age than women, but women live longer so they catch up with men and thus the total number of cases in men and women is equal. Women diagnosed with uterine or ovarian cancer before age 50 are at increased risk of colorectal cancer. Woman with a personal history of breast cancer have only a very slight increase in risk of colorectal cancer. The average age to develop colorectal cancer is 70 years, and 93% of cases occur in persons 50 years of age or older. You have a higher risk for colon cancer if you have:
Cancer elsewhere in the body.
Colorectal polypsCrohn's disease
Family history of colon cancer
Personal history of breast cancer
Ulcerative colitis.
What are the symptoms of colorectal cancer. Symptoms of colorectal cancer vary depending on the location of the cancer within the colon or rectum, though there may be no symptoms at all. The most common presenting symptom of colorectal cancer is rectal bleeding. Cancers arising from the left side of the colon generally cause bleeding, or in their late stages may cause constipation, abdominal pain, and obstructive symptoms. On the other hand, right-sided colon lesions may produce vague abdominal aching, but are unlikely to present with obstruction or altered bowel habit. Other symptoms such as weakness, weight loss, or anemia resulting from chronic blood loss may accompany cancer of the right side of the colon.
If your doctor learns that you do have colorectal cancer, more tests will be done to see if the cancer has spread. Colonoscopy is currently the only test recommended for colorectal cancer screening in average-risk persons at 10 year intervals. Colonoscopic surveillance (also called screening colonoscopy) needs to be available at more frequent intervals for individuals at high risk for colon cancer (for instance, those with a personal history of colorectal cancer or adenomatous polyps; family history of colorectal cancer; non-hereditary polyposis; colorectal cancer; or a pre-disposing condition such as inflammatory bowel disease.
The first step to avoiding this ailment is prevention with regular tests at the doctor, but there are other ways of getting around this disease in between checkups. Nevertheless, it appears that increasing the fiber content in the Western diet would be useful in the primary prevention of colorectal cancer. It is recommended that physical activity messages promoting at least 30-45 minutes of moderate to vigorous activity on most days of the week be included in primary prevention interventions for cancer. The population prevalence for meeting proposed physical activity criteria for colon cancer prevention is low and much lower than that related to the more generic public health recommendations.
Our bodies need lots of calcium and not only for building strong bones. Colon cancer prevention is one of the most exciting uses for calcium. However, instead of using calcium supplements, this study relied on low-fat dairy products to supply 1,200mg calcium per day. Investigators found this amount of calcium decreased the incidence of changes in the cells lining the colon, which is often seen in the initial stages of colon cancer. A significant protective factor is adequate dietary calcium intake during the period of maximum growth, ages 9 and 25 years, so that proper peak bone mass is achieved by age 20and 30 years and maintained until mid-life, with only slow bone loss in the following years. As already noted, dietary surveys indicate a significant gap between the recommended calcium intake and the actual intake in the United States in the critical years of adolescence and young adulthood and later in life.
Article Source: http://www.articlesbase.com/cancer-articles/risks-of-colon-cancer-in-women-and-men-468765.html
Colorectal cancer is the second most common cancer killer overall and third most common cause of cancer-related death in the United States in both males and females. Who is at risk for colorectal cancer. Men tend to get colorectal cancer at an earlier age than women, but women live longer so they catch up with men and thus the total number of cases in men and women is equal. Women diagnosed with uterine or ovarian cancer before age 50 are at increased risk of colorectal cancer. Woman with a personal history of breast cancer have only a very slight increase in risk of colorectal cancer. The average age to develop colorectal cancer is 70 years, and 93% of cases occur in persons 50 years of age or older. You have a higher risk for colon cancer if you have:
Cancer elsewhere in the body.
Colorectal polypsCrohn's disease
Family history of colon cancer
Personal history of breast cancer
Ulcerative colitis.
What are the symptoms of colorectal cancer. Symptoms of colorectal cancer vary depending on the location of the cancer within the colon or rectum, though there may be no symptoms at all. The most common presenting symptom of colorectal cancer is rectal bleeding. Cancers arising from the left side of the colon generally cause bleeding, or in their late stages may cause constipation, abdominal pain, and obstructive symptoms. On the other hand, right-sided colon lesions may produce vague abdominal aching, but are unlikely to present with obstruction or altered bowel habit. Other symptoms such as weakness, weight loss, or anemia resulting from chronic blood loss may accompany cancer of the right side of the colon.
If your doctor learns that you do have colorectal cancer, more tests will be done to see if the cancer has spread. Colonoscopy is currently the only test recommended for colorectal cancer screening in average-risk persons at 10 year intervals. Colonoscopic surveillance (also called screening colonoscopy) needs to be available at more frequent intervals for individuals at high risk for colon cancer (for instance, those with a personal history of colorectal cancer or adenomatous polyps; family history of colorectal cancer; non-hereditary polyposis; colorectal cancer; or a pre-disposing condition such as inflammatory bowel disease.
The first step to avoiding this ailment is prevention with regular tests at the doctor, but there are other ways of getting around this disease in between checkups. Nevertheless, it appears that increasing the fiber content in the Western diet would be useful in the primary prevention of colorectal cancer. It is recommended that physical activity messages promoting at least 30-45 minutes of moderate to vigorous activity on most days of the week be included in primary prevention interventions for cancer. The population prevalence for meeting proposed physical activity criteria for colon cancer prevention is low and much lower than that related to the more generic public health recommendations.
Our bodies need lots of calcium and not only for building strong bones. Colon cancer prevention is one of the most exciting uses for calcium. However, instead of using calcium supplements, this study relied on low-fat dairy products to supply 1,200mg calcium per day. Investigators found this amount of calcium decreased the incidence of changes in the cells lining the colon, which is often seen in the initial stages of colon cancer. A significant protective factor is adequate dietary calcium intake during the period of maximum growth, ages 9 and 25 years, so that proper peak bone mass is achieved by age 20and 30 years and maintained until mid-life, with only slow bone loss in the following years. As already noted, dietary surveys indicate a significant gap between the recommended calcium intake and the actual intake in the United States in the critical years of adolescence and young adulthood and later in life.
Article Source: http://www.articlesbase.com/cancer-articles/risks-of-colon-cancer-in-women-and-men-468765.html
Ovarian Cancer - Don't Ignore the Warning Signs
Around 1.5 percent of women are likely to develop ovarian cancer at some stage of their life. It is less common than breast cancer but is considered as the most serious and fatal of all gynecological cancers.
The reason for this is that the cancer is usually advanced before it is diagnosed, making treatment difficult. The ovaries cannot be easily examined and, because the warning signs are unclear, late diagnosis is common.
Because of the lack of screening tests available, it is imperative to know the early symptoms and the possible risk factors.
Understanding ovarian cancer
The ovaries are two small organs that are a part of the female reproductive system and they are situated each side of the uterus. These ovaries contain germ cells that become eggs which are released when the woman menstruates.
They also produce estrogen and progesterone, the hormones that adjust the menstrual cycle and have an effect on the growth of breasts and body hair as well as affecting the development of the female body shape.
What types of tumors are there?
This normally happens in an organised manner but occasionally they grow abnormally and form a growth that we know as a tumor.
This tumor may be benign or it may be malignant. If it is benign, it is not cancerous and does not spread to other parts of the body. A malignant tumor, on the other hand, is cancerous and will often spread, making mestastases or secondary cancers.
Ovarian cancer is malignant and can occur in either one or both of the ovaries. There are three main groups that are related to the cells where the cancer starts.
Epithelial ovarian cancer, as its name implies, grows in the epithelium which is the surface of the ovary. It is the most common and accounts for around 90 percent of ovarian cancer. It mainly affects post menopausal women.
Another kind of epithelial tumor is a borderline tumor which grows much more slowly than its regular counterpart. These can normally be removed successfully even if diagnosed at an advanced stage.
There is a very rare form of ovarian cancer called germ cell ovarian cancer that starts in the cells that develop into eggs. This only accounts for about 5 percent of ovarian cancers and usually occurs only in women under 30.
The other five percent of ovarian cancers are generally sex-chord stromal cell ovarian cancer that affects the ovary cells responsible for female hormones. It can affect women of all ages.
Who is at risk of getting ovarian cancer?
The cause of ovarian cancer is unknown but there are some risk factors that have been identified through research. Although having these risk factors may increase your chances of developing ovarian cancer, they do not mean that you will necessarily get the disease. However, knowledge of these risk factors can be helpful. If you are concerned by having any of these risk factors, it is important to talk to your healthcare professional.
Factors that may increase your risk of ovarian cancer include:
Age- Around 90 percent of ovarian cancers affect women over 40.
Cultural background - Caucasian women in western society have higher rates of ovarian cancer than African or Asian women.
Number of pregnancies - Women who have never been pregnant appear to have a higher risk of ovarian cancer.
Family history - Between 5 and 10% of ovarian cancers are genetic. Researchers believe that the genes responsible for breast cancer (BRCA1 and BRCA2) are involved in almost all cases of familial ovarian cancer as well as familial breast cancer. It is also thought that these same damaged genes may be responsible for some endometrial and colon cancers. If you are genetically predisposed to any ovarian, breast, endometrial or colon cancers, you may have an increased risk of getting ovarian cancer.
Infertility and taking fertility drugs - Women who have had fertility drugs may be at a higher risk although infertility itself is a risk factor so this cannot be taken as a clear indication.
Hormone Replacement Therapy - The use of estrogen only HRT which is usually when you have had a hysterectomy, has been identified as a possible risk factor for ovarian cancer, particularly if you have been on this therapy for over ten years.
Lifestyle factors - Obesity is a risk factor associated with ovarian cancer as is a diet that is high in fat.
Can I reduce the risk of ovarian cancer?
Currently, there are no known procedures to prevent or detect early ovarian cancer but there are ways to reduce the risks. Some of these are:
Oral contraceptives - Research has found that the use of oral contraceptives can cut the risk of ovarian cancer by up to 60 percent if taken for a period of five years during your life.
Pregnancy and breastfeeding - Breastfeeding delays ovulation after childbirth and therefore decreases your risk of ovarian cancer. However, there is no guarantee that breastfeeding will stop you from developing ovarian cancer.
Enjoy a low fat diet - A high fat diet has been identified as a risk factor in ovarian cancer. Therefore, it makes sense to stick to a low fat diet with lots of fresh fruit and vegetables.
Tubal ligation or hysterectomy - These operations are only performed with a valid medical reason but it is believed that they both reduce the risk of ovarian cancer.
People with a strong family history of ovarian cancer may opt to speak to a genetic counselor that can assess whether you are at risk of developing the disease. If your family history suggests the damaged genes associated with ovarian, breast, endometrial, or colon cancer, it may be wise to have genetic testing. If these tests show the damaged BRCA1 or BRCA2 genes, you may be refe.rred to a gynecological oncologist to consider ways to reduce your risk.
Early symptoms of ovarian cancer
Because there is no screening test available for ovarian cancer, it is recommended that you have a regular pelvic vaginal checkup to see if there are any changes in your ovaries. It is also vital that you consult your healthcare specialist if you notice any possible signs of this illness. Because the symptoms are often common to many other medical conditions, diagnosis of ovarian cancer can be difficult
However, if you have any of the following symptoms that are unusual for you and that persist for more than a week, see your doctor without delay.
Some symptoms of ovarian cancer may include:
Stomach discomfort of pain in the pelvic area
Persistent nausea or wind.
Feeling constantly bloated or ‘full'.
Unexplained weight gain.
Loss of appetite or unexplained weight loss
Bowel changes
Frequency or urgency in urination
Lethargy.
Pain during intercourse.
Unexplained vaginal bleeding.
Sometimes, ovarian cancers are wrongly diagnosed as irritable bowel syndrome or menopause so if you are concerned, ask to be referred to a gynecological oncologist who can order tests to rule out ovarian cancer. It is rare that these symptoms will be ovarian cancer but if it is, early detection gives an excellent chance of survival.
Diagnosing ovarian cancer
If your doctor suspects ovarian cancer, you will be referred to a gynecological oncologist who will organize tests which may include any or all of the following:
An internal pelvic examination.
Blood tests
Chest and stomach x-rays.
A barium enema to rule out bowel problems
Ultrasound scans
If the results show a likelihood of ovarian cancer, you will be recommended to have an operation to confirm the diagnosis (none of the abovementioned tests can be sure). During the operation, if the surgeon finds ovarian cancer, they will normally remove the cancer as well as the ovaries.
It is important to understand before the surgery that this may happen so learn all you can about your illness and the outcomes before the operation.
Anne Wolski has worked in the health and welfare industry for more than 30 years. She is a co-director of http://www.magnetic-health-online.com and http://www.betterhealthshoppe.com which are both information portals with many interesting medical articles. She is also an associate of http://www.timzbiz.com which features many articles on internet marketing and resources.
Article Source: http://www.articlesbase.com/health-articles/ovarian-cancer-dont-ignore-the-warning-signs-38725.html
The reason for this is that the cancer is usually advanced before it is diagnosed, making treatment difficult. The ovaries cannot be easily examined and, because the warning signs are unclear, late diagnosis is common.
Because of the lack of screening tests available, it is imperative to know the early symptoms and the possible risk factors.
Understanding ovarian cancer
The ovaries are two small organs that are a part of the female reproductive system and they are situated each side of the uterus. These ovaries contain germ cells that become eggs which are released when the woman menstruates.
They also produce estrogen and progesterone, the hormones that adjust the menstrual cycle and have an effect on the growth of breasts and body hair as well as affecting the development of the female body shape.
What types of tumors are there?
This normally happens in an organised manner but occasionally they grow abnormally and form a growth that we know as a tumor.
This tumor may be benign or it may be malignant. If it is benign, it is not cancerous and does not spread to other parts of the body. A malignant tumor, on the other hand, is cancerous and will often spread, making mestastases or secondary cancers.
Ovarian cancer is malignant and can occur in either one or both of the ovaries. There are three main groups that are related to the cells where the cancer starts.
Epithelial ovarian cancer, as its name implies, grows in the epithelium which is the surface of the ovary. It is the most common and accounts for around 90 percent of ovarian cancer. It mainly affects post menopausal women.
Another kind of epithelial tumor is a borderline tumor which grows much more slowly than its regular counterpart. These can normally be removed successfully even if diagnosed at an advanced stage.
There is a very rare form of ovarian cancer called germ cell ovarian cancer that starts in the cells that develop into eggs. This only accounts for about 5 percent of ovarian cancers and usually occurs only in women under 30.
The other five percent of ovarian cancers are generally sex-chord stromal cell ovarian cancer that affects the ovary cells responsible for female hormones. It can affect women of all ages.
Who is at risk of getting ovarian cancer?
The cause of ovarian cancer is unknown but there are some risk factors that have been identified through research. Although having these risk factors may increase your chances of developing ovarian cancer, they do not mean that you will necessarily get the disease. However, knowledge of these risk factors can be helpful. If you are concerned by having any of these risk factors, it is important to talk to your healthcare professional.
Factors that may increase your risk of ovarian cancer include:
Age- Around 90 percent of ovarian cancers affect women over 40.
Cultural background - Caucasian women in western society have higher rates of ovarian cancer than African or Asian women.
Number of pregnancies - Women who have never been pregnant appear to have a higher risk of ovarian cancer.
Family history - Between 5 and 10% of ovarian cancers are genetic. Researchers believe that the genes responsible for breast cancer (BRCA1 and BRCA2) are involved in almost all cases of familial ovarian cancer as well as familial breast cancer. It is also thought that these same damaged genes may be responsible for some endometrial and colon cancers. If you are genetically predisposed to any ovarian, breast, endometrial or colon cancers, you may have an increased risk of getting ovarian cancer.
Infertility and taking fertility drugs - Women who have had fertility drugs may be at a higher risk although infertility itself is a risk factor so this cannot be taken as a clear indication.
Hormone Replacement Therapy - The use of estrogen only HRT which is usually when you have had a hysterectomy, has been identified as a possible risk factor for ovarian cancer, particularly if you have been on this therapy for over ten years.
Lifestyle factors - Obesity is a risk factor associated with ovarian cancer as is a diet that is high in fat.
Can I reduce the risk of ovarian cancer?
Currently, there are no known procedures to prevent or detect early ovarian cancer but there are ways to reduce the risks. Some of these are:
Oral contraceptives - Research has found that the use of oral contraceptives can cut the risk of ovarian cancer by up to 60 percent if taken for a period of five years during your life.
Pregnancy and breastfeeding - Breastfeeding delays ovulation after childbirth and therefore decreases your risk of ovarian cancer. However, there is no guarantee that breastfeeding will stop you from developing ovarian cancer.
Enjoy a low fat diet - A high fat diet has been identified as a risk factor in ovarian cancer. Therefore, it makes sense to stick to a low fat diet with lots of fresh fruit and vegetables.
Tubal ligation or hysterectomy - These operations are only performed with a valid medical reason but it is believed that they both reduce the risk of ovarian cancer.
People with a strong family history of ovarian cancer may opt to speak to a genetic counselor that can assess whether you are at risk of developing the disease. If your family history suggests the damaged genes associated with ovarian, breast, endometrial, or colon cancer, it may be wise to have genetic testing. If these tests show the damaged BRCA1 or BRCA2 genes, you may be refe.rred to a gynecological oncologist to consider ways to reduce your risk.
Early symptoms of ovarian cancer
Because there is no screening test available for ovarian cancer, it is recommended that you have a regular pelvic vaginal checkup to see if there are any changes in your ovaries. It is also vital that you consult your healthcare specialist if you notice any possible signs of this illness. Because the symptoms are often common to many other medical conditions, diagnosis of ovarian cancer can be difficult
However, if you have any of the following symptoms that are unusual for you and that persist for more than a week, see your doctor without delay.
Some symptoms of ovarian cancer may include:
Stomach discomfort of pain in the pelvic area
Persistent nausea or wind.
Feeling constantly bloated or ‘full'.
Unexplained weight gain.
Loss of appetite or unexplained weight loss
Bowel changes
Frequency or urgency in urination
Lethargy.
Pain during intercourse.
Unexplained vaginal bleeding.
Sometimes, ovarian cancers are wrongly diagnosed as irritable bowel syndrome or menopause so if you are concerned, ask to be referred to a gynecological oncologist who can order tests to rule out ovarian cancer. It is rare that these symptoms will be ovarian cancer but if it is, early detection gives an excellent chance of survival.
Diagnosing ovarian cancer
If your doctor suspects ovarian cancer, you will be referred to a gynecological oncologist who will organize tests which may include any or all of the following:
An internal pelvic examination.
Blood tests
Chest and stomach x-rays.
A barium enema to rule out bowel problems
Ultrasound scans
If the results show a likelihood of ovarian cancer, you will be recommended to have an operation to confirm the diagnosis (none of the abovementioned tests can be sure). During the operation, if the surgeon finds ovarian cancer, they will normally remove the cancer as well as the ovaries.
It is important to understand before the surgery that this may happen so learn all you can about your illness and the outcomes before the operation.
Anne Wolski has worked in the health and welfare industry for more than 30 years. She is a co-director of http://www.magnetic-health-online.com and http://www.betterhealthshoppe.com which are both information portals with many interesting medical articles. She is also an associate of http://www.timzbiz.com which features many articles on internet marketing and resources.
Article Source: http://www.articlesbase.com/health-articles/ovarian-cancer-dont-ignore-the-warning-signs-38725.html
Human Papilloma Virus and Cancers
In recent years, it has become clear that certain types of human cancers have a viral component to their etiology. Cancers due to Human Papilloma Virus (HPV) are most common among these. This has been a study of intense research for number of years. Specific types of HPV genotypes were found to be the causative agents of some common cancers, most notable invasive cervical carcinoma. Apart from this anogenital cancer, HPV’s are also causally associated with other anogenital cancers such as cancers of vulva, vagina, penis and anus. HPV is also responsible for approximately 20-30% of head and neck cancers [1].
Association OF HPV with Cervical cancer
The link between HPV and cervical cancer is now established beyond doubts. Many epidemiological [2], [3] and molecular evidences [4] suggest the causal association of HPV’s with cervical cancer. It has been estimated that about 500,000 women acquire cervical cancers every year and 75% of this are from developing countries. In United States about 13000 cervical cancer cases are diagnosed every year and about 7000 deaths annually from prevalent disease [5].
Evidence suggests that the great majority of all grades of cervical intraepithelial neoplasia can be attributed to cancer-associated types of HPV infections
[3]. It has been estimated that only about 10% of the HPV patients would develop cervical dysplasia and of these only few people would develop cervical cancer. Studies conducted on HPV DNA in a variety of genital lesions suggested that HPV types 16 and 18 are most closely associated with risk of genital cancers [4] and some of HPV types are considered to be more prevalent among cervical cancer patients in a specific geographical areas; HPV 45 in Western African [6].
The development of cervical cancer is associated with factors other than just high risk HPV infection. Factors like impaired cell mediated immunity, long term use of contraceptives and smoking also increase the risk of gaining and the persistence of HPV types which in turn may lead to cervical cancers [7],[8].
Association of HPV with other anogenital cancers
Strong links between HPV and anogenital cancers such as penile, anal, vulvar cancers have been demonstrated by many studies. These cancers are formed from lesions develop in the vagina, vulva, penis and anus as the result of sexual contact [9]. But the exact role of HPV in the natural history of anal squamous intraepithelial lesions is still unknown [10].
Studies indicate that about 1% of sexually active adults in the United States show visible genital wart and about 15 % have sub clinical infection. The most commonly detected HPV types were found to be HPV 16 and 18 [11]. But, HPV types 56, 59-64 and 71 also have been isolated in vulvar intraepithelial neoplasia [12] .
Association of HPV with head and neck cancer
The term head and neck cancer refer to the cancers in the oral cavity, lip, nose, para nasal sinuses, naso-pharynx, oro-parynx, larynx, oesophagus, salivary glands, soft tissues of the neck and ear. Oral cancer is the sixth most prevalent cancer worldwide and about 620,000 patients are diagnosed with cancer of oral cavity every year [13]. Many studies have found evidence suggestive of a role for human papilloma virus in head and neck cancer [14],[15]. Though the exact mode of transmission of HPV infection in the head and neck region has not been determined, it’s association with sexual behavior and perinatal transmission have been demonstrated [16].
During the pathogenesis of HPV, it enters to the host through the mucosal epithelial layer surface. Oral mucosa resembles the mucosa of the genital region in their histological structure. As the correlation between HPV and cervical cancer are well established, the resemblance of the mucosal histology led to the suggestion that HPV could play a role in the development of benign and malignant lesions of the oral mucosa [17].
After the first report of papilloma virus in tongue carcinoma[14], many studies have shown the presence of HPV DNA in oral cavity [15] and head and neck cancer [13]. The most prevalent HPV types in these were found to be HPV 16 and 18. Further epidemiologic and molecular investigation should be carried out to establish a precise relationship between HPV and head and neck cancer.
HPV INDUCED CANCER DETECTION
Detective measures to date have centered on screening programs for HPV induced cancers. The most common and the traditional way of screening for cervical cancer and cervical dysplasia are to conduct a pap smear test. This has significantly reduced the incidence of cervical cancers in recent years. If the result is turned out to be positive, then the colposcopy would be carried. Since cervical cancer and anal cancer resembles in their biological features, it has been observed that screening for anal high grade squamous intraepithelial lesions with anal pap smear allows detecting individuals at risk of developing anal cancers. To obtain a confirmatory result, an anoscopic examination should be performed [18, 19].
Detection of earlier stage of head and neck cancers as well as premalignant lesions can be done by regular physical examinations by the doctor. Any abnormalities should be further evaluated. An endoscopy is performed on the samples obtained from throat, larynx, and upper esophagus. Computed tomographic (CT) scans, magnetic resonances imaging (MRI) scans or ultrasounds could be performed to identify the size and extent to which the cancer has spread from its site of origin [20].
No standard screening tests are followed for vulvar cancers. In vulvar cancer lymph node pathologic status is the most important predictive factor. A study conducted by De Ceccoc et al indicated that Lymphoscintigraphy and sentinel-node biopsy under gamma-detecting probe guidance are easy and reliable methods for the detection of sentinel node in early vulvar cancer [21]. Coloscopy can also be used to detect abnormalities on vulvar epethilia [19].
The above mentioned tests cannot be used to detect the presence or absence of the virus which would eventually cause a cancer. A test based on the hybrid capture technologies is now available to detect 13 cancer causing kinds of HPV. This technology is based on the principle of signal amplification of a hybrid species produced by RNA probes fixed with HPV DNA [22]. Polymerase chain reaction is one of the most sensitive tests for HPV DNA detection [23]. But Zhao M. et al suggest that there could be limitations in this method when applying to a broad population [24]. Studies indicate that HPV DNA testing is one of the most effective tests which could be used for the prevention of cervical cancer [25].
In a study conducted by Reid et al, to compare the efficacy of cervical cytology, cervicography and/or DNA hybridization for cervical cancer screening, showed that none of the tests succeeded in identifying all the abnormalities [26].
REFERENCES
1. I. Benjamin Paz, N.C., Tamara Odom-Maryon, Yuan Xie, Sharon P. Wilczynski,, Human papillomavirus (HPV) in head and neck cancer. Cancer, 1997. 79(3): p. 595-604.
2. Koutsky, L.A., et al., A cohort study of the risk of cervical intraepithelial neoplasia grade 2 or 3 in relation to papillomavirus infection. N Engl J Med, 1992. 327(18): p. 1272-8.
3. Schiffman, M.H., et al., Epidemiologic evidence showing that human papillomavirus infection causes most cervical intraepithelial neoplasia. J Natl Cancer Inst, 1993. 85(12): p. 958-64.
4. JC Macnab, S.W., JW Cordiner, and JB Clements, Human papillomavirus in clinically and histologically normal tissue of patients with genital cancer. The New England Journal of Medicine, 1986. 315(17): p. 1052-1058.
5. Parkin, D.M., P. Pisani, and J. Ferlay, Estimates of the worldwide incidence of 25 major cancers in 1990. Int J Cancer, 1999. 80(6): p. 827-41.
6. Bosch, F.X., et al., Prevalence of human papillomavirus in cervical cancer: a worldwide perspective. International biological study on cervical cancer (IBSCC) Study Group. J Natl Cancer Inst, 1995. 87(11): p. 796-802.
7. Calore, E.E., S.M. Pereira, and M.J. Cavaliere, Progression of cervical lesions in HIV-seropositive women: a cytological study. Diagn Cytopathol, 2001. 24(2): p. 117-9.
8. Brisson, J., et al., Risk factors for cervical intraepithelial neoplasia: differences between low- and high-grade lesions. Am J Epidemiol, 1994. 140(8): p. 700-10.
9. Jung, W.W., et al., Strategies against human papillomavirus infection and cervical cancer. J Microbiol, 2004. 42(4): p. 255-66.
10. Palefsky, J.M., et al., Detection of human papillomavirus DNA in anal intraepithelial neoplasia and anal cancer. Cancer Res, 1991. 51(3): p. 1014-9.
11. Koutsky, P., Laura, Epidemiology of Genital Human Papillomavirus Infection. The American Journal of Medicine, 1997. 102(5, Supplement 1): p. 3-8.
12. Longuet, M., S. Beaudenon, and G. Orth, Two novel genital human papillomavirus (HPV) types, HPV68 and HPV70, related to the potentially oncogenic HPV39. J. Clin. Microbiol., 1996. 34(3): p. 738-744.
13. Syrjanen, S., Human papillomavirus (HPV) in head and neck cancer. J Clin Virol, 2005. 32 Suppl 1: p. S59-66.
14. de Villiers, E.M., et al., Papillomavirus DNA in human tongue carcinomas. Int J Cancer, 1985. 36(5): p. 575-8.
15. Palefsky, J.M., et al., Association between proliferative verrucous leukoplakia and infection with human papillomavirus type 16. J Oral Pathol Med, 1995. 24(5): p. 193-7.
16. Szentirmay, Z., et al., Human papillomavirus in head and neck cancer: molecular biology and clinicopathological correlations. Cancer Metastasis Rev, 2005. 24(1): p. 19-34.
17. Woods, K.V., et al., Analysis of human papillomavirus DNA in oral squamous cell carcinomas. J Oral Pathol Med, 1993. 22(3): p. 101-8.
18. Sheary B, D.L., Cervical screening and human papillomavirus. Aust Fam Physician., 2005. 34(7): p. 578-80.
19. JD., O., Genitoanal papillomavirus infection--a diagnostic and therapeutic dilemma. Semin Dermatol., 1990. 9(2): p. 141-7.
20. Antunes, J.L.F., et al., Trends and spatial distribution of oral cancer mortality in Sao Paulo, Brazil, 1980-1998. Oral Oncology, 2001. 37(4): p. 345-350.
21. C De Cicco, M.S., M Bartolomei, C Grana, M Cremonesi, M Fiorenza, A Maggioni, L Bocciolone, C Mangioni, N Colombo and G Paganelli, Sentinel node biopsy in early vulvar cancer. British Journal of Cancer, 2000. 82: p. 295-299.
22. Thomas, R.J., Early Detection of Cervical Cancer -New diagnostics identify HPV. Modern Drug Discovery, 2000. 4: p. 57-58.
23. Miller CS, Z.M., White DK., Detection of HPV DNA in oral carcinoma using polymerase chain reaction together with in situ hybridization. Oral Surg Oral Med Oral Pathol., 1994. 77(5): p. 480-6.
24. Ming Zhao, E.R., Andre Lopes Carvalho, Wayne Koch, WeiWen Jiang, David Sidransky, Joseph Califano,, Feasibility of quantitative PCR-based saliva rinse screening of HPV for head and neck cancer. International Journal of Cancer, 2005. 117(4): p. 605-610.
25. Denny, L.A., Human papillomavirus testing and screening. Best Practice & Research Clinical Obstetrics & Gynaecology, 2005. 19(4): p. 501-15.
26. Harry, T.C.S., K.M., Evaluation of the Hybrid Capture human papillomavirus deoxyribonucleic acid detection test. American Journal of Obstetrics & Gynecology, 1996. 175(3): p. 758-9.
Article Source: http://www.articlesbase.com/cancer-articles/human-papilloma-virus-and-cancers-314912.html
Association OF HPV with Cervical cancer
The link between HPV and cervical cancer is now established beyond doubts. Many epidemiological [2], [3] and molecular evidences [4] suggest the causal association of HPV’s with cervical cancer. It has been estimated that about 500,000 women acquire cervical cancers every year and 75% of this are from developing countries. In United States about 13000 cervical cancer cases are diagnosed every year and about 7000 deaths annually from prevalent disease [5].
Evidence suggests that the great majority of all grades of cervical intraepithelial neoplasia can be attributed to cancer-associated types of HPV infections
[3]. It has been estimated that only about 10% of the HPV patients would develop cervical dysplasia and of these only few people would develop cervical cancer. Studies conducted on HPV DNA in a variety of genital lesions suggested that HPV types 16 and 18 are most closely associated with risk of genital cancers [4] and some of HPV types are considered to be more prevalent among cervical cancer patients in a specific geographical areas; HPV 45 in Western African [6].
The development of cervical cancer is associated with factors other than just high risk HPV infection. Factors like impaired cell mediated immunity, long term use of contraceptives and smoking also increase the risk of gaining and the persistence of HPV types which in turn may lead to cervical cancers [7],[8].
Association of HPV with other anogenital cancers
Strong links between HPV and anogenital cancers such as penile, anal, vulvar cancers have been demonstrated by many studies. These cancers are formed from lesions develop in the vagina, vulva, penis and anus as the result of sexual contact [9]. But the exact role of HPV in the natural history of anal squamous intraepithelial lesions is still unknown [10].
Studies indicate that about 1% of sexually active adults in the United States show visible genital wart and about 15 % have sub clinical infection. The most commonly detected HPV types were found to be HPV 16 and 18 [11]. But, HPV types 56, 59-64 and 71 also have been isolated in vulvar intraepithelial neoplasia [12] .
Association of HPV with head and neck cancer
The term head and neck cancer refer to the cancers in the oral cavity, lip, nose, para nasal sinuses, naso-pharynx, oro-parynx, larynx, oesophagus, salivary glands, soft tissues of the neck and ear. Oral cancer is the sixth most prevalent cancer worldwide and about 620,000 patients are diagnosed with cancer of oral cavity every year [13]. Many studies have found evidence suggestive of a role for human papilloma virus in head and neck cancer [14],[15]. Though the exact mode of transmission of HPV infection in the head and neck region has not been determined, it’s association with sexual behavior and perinatal transmission have been demonstrated [16].
During the pathogenesis of HPV, it enters to the host through the mucosal epithelial layer surface. Oral mucosa resembles the mucosa of the genital region in their histological structure. As the correlation between HPV and cervical cancer are well established, the resemblance of the mucosal histology led to the suggestion that HPV could play a role in the development of benign and malignant lesions of the oral mucosa [17].
After the first report of papilloma virus in tongue carcinoma[14], many studies have shown the presence of HPV DNA in oral cavity [15] and head and neck cancer [13]. The most prevalent HPV types in these were found to be HPV 16 and 18. Further epidemiologic and molecular investigation should be carried out to establish a precise relationship between HPV and head and neck cancer.
HPV INDUCED CANCER DETECTION
Detective measures to date have centered on screening programs for HPV induced cancers. The most common and the traditional way of screening for cervical cancer and cervical dysplasia are to conduct a pap smear test. This has significantly reduced the incidence of cervical cancers in recent years. If the result is turned out to be positive, then the colposcopy would be carried. Since cervical cancer and anal cancer resembles in their biological features, it has been observed that screening for anal high grade squamous intraepithelial lesions with anal pap smear allows detecting individuals at risk of developing anal cancers. To obtain a confirmatory result, an anoscopic examination should be performed [18, 19].
Detection of earlier stage of head and neck cancers as well as premalignant lesions can be done by regular physical examinations by the doctor. Any abnormalities should be further evaluated. An endoscopy is performed on the samples obtained from throat, larynx, and upper esophagus. Computed tomographic (CT) scans, magnetic resonances imaging (MRI) scans or ultrasounds could be performed to identify the size and extent to which the cancer has spread from its site of origin [20].
No standard screening tests are followed for vulvar cancers. In vulvar cancer lymph node pathologic status is the most important predictive factor. A study conducted by De Ceccoc et al indicated that Lymphoscintigraphy and sentinel-node biopsy under gamma-detecting probe guidance are easy and reliable methods for the detection of sentinel node in early vulvar cancer [21]. Coloscopy can also be used to detect abnormalities on vulvar epethilia [19].
The above mentioned tests cannot be used to detect the presence or absence of the virus which would eventually cause a cancer. A test based on the hybrid capture technologies is now available to detect 13 cancer causing kinds of HPV. This technology is based on the principle of signal amplification of a hybrid species produced by RNA probes fixed with HPV DNA [22]. Polymerase chain reaction is one of the most sensitive tests for HPV DNA detection [23]. But Zhao M. et al suggest that there could be limitations in this method when applying to a broad population [24]. Studies indicate that HPV DNA testing is one of the most effective tests which could be used for the prevention of cervical cancer [25].
In a study conducted by Reid et al, to compare the efficacy of cervical cytology, cervicography and/or DNA hybridization for cervical cancer screening, showed that none of the tests succeeded in identifying all the abnormalities [26].
REFERENCES
1. I. Benjamin Paz, N.C., Tamara Odom-Maryon, Yuan Xie, Sharon P. Wilczynski,, Human papillomavirus (HPV) in head and neck cancer. Cancer, 1997. 79(3): p. 595-604.
2. Koutsky, L.A., et al., A cohort study of the risk of cervical intraepithelial neoplasia grade 2 or 3 in relation to papillomavirus infection. N Engl J Med, 1992. 327(18): p. 1272-8.
3. Schiffman, M.H., et al., Epidemiologic evidence showing that human papillomavirus infection causes most cervical intraepithelial neoplasia. J Natl Cancer Inst, 1993. 85(12): p. 958-64.
4. JC Macnab, S.W., JW Cordiner, and JB Clements, Human papillomavirus in clinically and histologically normal tissue of patients with genital cancer. The New England Journal of Medicine, 1986. 315(17): p. 1052-1058.
5. Parkin, D.M., P. Pisani, and J. Ferlay, Estimates of the worldwide incidence of 25 major cancers in 1990. Int J Cancer, 1999. 80(6): p. 827-41.
6. Bosch, F.X., et al., Prevalence of human papillomavirus in cervical cancer: a worldwide perspective. International biological study on cervical cancer (IBSCC) Study Group. J Natl Cancer Inst, 1995. 87(11): p. 796-802.
7. Calore, E.E., S.M. Pereira, and M.J. Cavaliere, Progression of cervical lesions in HIV-seropositive women: a cytological study. Diagn Cytopathol, 2001. 24(2): p. 117-9.
8. Brisson, J., et al., Risk factors for cervical intraepithelial neoplasia: differences between low- and high-grade lesions. Am J Epidemiol, 1994. 140(8): p. 700-10.
9. Jung, W.W., et al., Strategies against human papillomavirus infection and cervical cancer. J Microbiol, 2004. 42(4): p. 255-66.
10. Palefsky, J.M., et al., Detection of human papillomavirus DNA in anal intraepithelial neoplasia and anal cancer. Cancer Res, 1991. 51(3): p. 1014-9.
11. Koutsky, P., Laura, Epidemiology of Genital Human Papillomavirus Infection. The American Journal of Medicine, 1997. 102(5, Supplement 1): p. 3-8.
12. Longuet, M., S. Beaudenon, and G. Orth, Two novel genital human papillomavirus (HPV) types, HPV68 and HPV70, related to the potentially oncogenic HPV39. J. Clin. Microbiol., 1996. 34(3): p. 738-744.
13. Syrjanen, S., Human papillomavirus (HPV) in head and neck cancer. J Clin Virol, 2005. 32 Suppl 1: p. S59-66.
14. de Villiers, E.M., et al., Papillomavirus DNA in human tongue carcinomas. Int J Cancer, 1985. 36(5): p. 575-8.
15. Palefsky, J.M., et al., Association between proliferative verrucous leukoplakia and infection with human papillomavirus type 16. J Oral Pathol Med, 1995. 24(5): p. 193-7.
16. Szentirmay, Z., et al., Human papillomavirus in head and neck cancer: molecular biology and clinicopathological correlations. Cancer Metastasis Rev, 2005. 24(1): p. 19-34.
17. Woods, K.V., et al., Analysis of human papillomavirus DNA in oral squamous cell carcinomas. J Oral Pathol Med, 1993. 22(3): p. 101-8.
18. Sheary B, D.L., Cervical screening and human papillomavirus. Aust Fam Physician., 2005. 34(7): p. 578-80.
19. JD., O., Genitoanal papillomavirus infection--a diagnostic and therapeutic dilemma. Semin Dermatol., 1990. 9(2): p. 141-7.
20. Antunes, J.L.F., et al., Trends and spatial distribution of oral cancer mortality in Sao Paulo, Brazil, 1980-1998. Oral Oncology, 2001. 37(4): p. 345-350.
21. C De Cicco, M.S., M Bartolomei, C Grana, M Cremonesi, M Fiorenza, A Maggioni, L Bocciolone, C Mangioni, N Colombo and G Paganelli, Sentinel node biopsy in early vulvar cancer. British Journal of Cancer, 2000. 82: p. 295-299.
22. Thomas, R.J., Early Detection of Cervical Cancer -New diagnostics identify HPV. Modern Drug Discovery, 2000. 4: p. 57-58.
23. Miller CS, Z.M., White DK., Detection of HPV DNA in oral carcinoma using polymerase chain reaction together with in situ hybridization. Oral Surg Oral Med Oral Pathol., 1994. 77(5): p. 480-6.
24. Ming Zhao, E.R., Andre Lopes Carvalho, Wayne Koch, WeiWen Jiang, David Sidransky, Joseph Califano,, Feasibility of quantitative PCR-based saliva rinse screening of HPV for head and neck cancer. International Journal of Cancer, 2005. 117(4): p. 605-610.
25. Denny, L.A., Human papillomavirus testing and screening. Best Practice & Research Clinical Obstetrics & Gynaecology, 2005. 19(4): p. 501-15.
26. Harry, T.C.S., K.M., Evaluation of the Hybrid Capture human papillomavirus deoxyribonucleic acid detection test. American Journal of Obstetrics & Gynecology, 1996. 175(3): p. 758-9.
Article Source: http://www.articlesbase.com/cancer-articles/human-papilloma-virus-and-cancers-314912.html
An Overview of Cancer
Cancer is second only to cardiovascular disease as the leading cause of death in the Western world.
Although Cancer is primarily a disease of the elderly with more than 60% of deaths from cancer occurring in those over the age of 65, cancer can strike even the youngest of children.
Cancer appears to occur when the growth of cells in the body is out of control and cells divide too rapidly. Cancer can develop in almost any organ or tissue, such as the lung, colon, breast, skin, bones, or nerve tissue.
Most common sites are:
Prostrate 24%
Breast 13%
Lung 13%
Colon and Rectum 9%
Bladder 3%
Uterus 2.5%
The cause of Cancer is believed to be a combination of genetic factors and outside carcinogens such as tobacco, viruses, infection, asbestos, vinyl chloride, inappropriate diet.
Cancer often has no specific symptoms, so it is important that you limit your risk factors and undergo appropriate cancer screening. The signs and symptoms will depend on where the cancer is, the size of the cancer, and how much it affects the nearby organs or structures.
If a cancer spreads (metastasizes), then symptoms may appear in different parts of the body. As a cancer grows, it begins to push on nearby organs, blood vessels, and nerves. If the cancer is in a critical area, such as certain parts of the brain, even the smallest tumor can cause early symptoms.
But sometimes cancers start in places where it does not cause any symptoms until the cancer has grown quite large. Pancreatic cancers, for example, do not usually grow large enough to be felt from the outside of the body.
By the time a pancreatic cancer causes these signs or symptoms, it has usually reached an advanced stage.
A cancer may also cause symptoms common to many other problems, such as; fever, fatigue and weight loss. This may be because the cancer uses up much of the body s energy or it may cause the release of substances which affect metabolism.
Some lung cancers make hormone-like substances that affect blood calcium levels, affecting nerves and muscles and causing weakness and dizziness.
It is important to know what some of the general (non-specific) signs and symptoms of cancer are, but remember that having any of these does not mean that you have cancer.
Most cancers can be treated and some cured, depending on the specific type, location, and stage. The earlier the cancer is found, the better the prognosis.
A good example of the importance of finding cancer early is melanoma skin cancer. Skin cancer can be easy to remove if it has not grown deep into the skin, and the 5-year survival rate (percentage of people living at least 5 years after diagnosis) at this stage is nearly100%.
Screening for breast cancer with mammograms has been shown to reduce the average stage of diagnosis of breast cancer in a population.
Colorectal cancer can be detected through fecal occult blood testing and colonoscopy, which reduces both colon cancer incidence and mortality, presumably through the detection and removal of pre-malignant polyps.
Similarly, cervical cytology testing (using the Pap smear) leads to the identification and excision of precancerous lesions.
Testicular self-examination is recommended for men beginning at the age of 15 years to detect testicular cancer.
SIGNS and SYMPTOMS
Pain may be an early symptom with some cancers such as bone cancers or testicular cancer.
Long-term constipation, diarrhea, or a change in the size of the stool may be a sign of colon cancer.
Pain with urination, blood in the urine, or a change in bladder function (such as more frequent or less frequent urination) could be related to bladder or prostate cancer.
Skin cancers may bleed and look like sores that do not heal.
A long-lasting sore in the mouth could be an oral cancer and should be dealt with right away, especially in patients who smoke, chew tobacco, or frequently drink alcohol.
Sores on the penis or vagina may either be signs of infection or an early cancer, and should not be overlooked.
Unusual bleeding can happen in either early or advanced cancer.
Blood in the sputum (phlegm) may be a sign of lung cancer.
Blood in the stool (or a dark or black stool) could be a sign of colon or rectal cancer.
Blood in the urine may be a sign of bladder or kidney cancer.
A bloody discharge from the nipple may be a sign of breast cancer.
Many cancers can be felt through the skin, mostly in the breast, testicle, lymph nodes (glands), and the soft tissues of the body. A lump or thickening may be an early or late sign of cancer.
While they commonly have other causes, indigestion or swallowing problems may be a sign of cancer of the esophagus, stomach, or pharynx (throat).
A cough that does not go away may be a sign of lung cancer.
A cancer may be suspected for a variety of reasons, but the definitive diagnosis of most malignancies must be confirmed by histological examination of the cancerous cells by a pathologist.
TREATMENT
Once diagnosed, cancer is usually treated with a combination of surgery, chemotherapy and radiotherapy.
Radiation therapy may be used to treat almost every type of solid tumor, including cancers of the brain, breast, cervix, larynx, lung, pancreas, prostate, skin, stomach, uterus, or soft tissue sarcomas.
Most forms of chemotherapy target all rapidly dividing cells and are not specific for cancer cells, although some degree of specificity may come from the inability of many cancer cells to repair DNA damage, while normal cells generally can.
Contemporary methods for generating an immune response against tumours include intravesical BCG immunotherapy for superficial bladder cancer, and use of interferons and other cytokines to induce an immune response in renal cell carcinoma and melanoma patients.
Pain medication, such as morphine and oxycodone, and anti-emetics, drugs to suppress nausea and vomiting, are very commonly used in patients with cancer-related symptoms. transmission and disease.
Advances in cancer research have made a vaccine designed to prevent cancer available. The vaccine protects against four HPV types, which together cause 70% of cervical cancers and 90% of genital warts.
The consensus on diet and cancer is that obesity increases the risk of developing cancer. The cancer-fighting components of food are also proving to be more numerous and varied than previously understood, so patients are increasingly being advised to consume fresh, unprocessed fruits and vegetables for maximal health benefits.
Article Source: http://www.articlesbase.com/cancer-articles/an-overview-of-cancer-427004.html
Although Cancer is primarily a disease of the elderly with more than 60% of deaths from cancer occurring in those over the age of 65, cancer can strike even the youngest of children.
Cancer appears to occur when the growth of cells in the body is out of control and cells divide too rapidly. Cancer can develop in almost any organ or tissue, such as the lung, colon, breast, skin, bones, or nerve tissue.
Most common sites are:
Prostrate 24%
Breast 13%
Lung 13%
Colon and Rectum 9%
Bladder 3%
Uterus 2.5%
The cause of Cancer is believed to be a combination of genetic factors and outside carcinogens such as tobacco, viruses, infection, asbestos, vinyl chloride, inappropriate diet.
Cancer often has no specific symptoms, so it is important that you limit your risk factors and undergo appropriate cancer screening. The signs and symptoms will depend on where the cancer is, the size of the cancer, and how much it affects the nearby organs or structures.
If a cancer spreads (metastasizes), then symptoms may appear in different parts of the body. As a cancer grows, it begins to push on nearby organs, blood vessels, and nerves. If the cancer is in a critical area, such as certain parts of the brain, even the smallest tumor can cause early symptoms.
But sometimes cancers start in places where it does not cause any symptoms until the cancer has grown quite large. Pancreatic cancers, for example, do not usually grow large enough to be felt from the outside of the body.
By the time a pancreatic cancer causes these signs or symptoms, it has usually reached an advanced stage.
A cancer may also cause symptoms common to many other problems, such as; fever, fatigue and weight loss. This may be because the cancer uses up much of the body s energy or it may cause the release of substances which affect metabolism.
Some lung cancers make hormone-like substances that affect blood calcium levels, affecting nerves and muscles and causing weakness and dizziness.
It is important to know what some of the general (non-specific) signs and symptoms of cancer are, but remember that having any of these does not mean that you have cancer.
Most cancers can be treated and some cured, depending on the specific type, location, and stage. The earlier the cancer is found, the better the prognosis.
A good example of the importance of finding cancer early is melanoma skin cancer. Skin cancer can be easy to remove if it has not grown deep into the skin, and the 5-year survival rate (percentage of people living at least 5 years after diagnosis) at this stage is nearly100%.
Screening for breast cancer with mammograms has been shown to reduce the average stage of diagnosis of breast cancer in a population.
Colorectal cancer can be detected through fecal occult blood testing and colonoscopy, which reduces both colon cancer incidence and mortality, presumably through the detection and removal of pre-malignant polyps.
Similarly, cervical cytology testing (using the Pap smear) leads to the identification and excision of precancerous lesions.
Testicular self-examination is recommended for men beginning at the age of 15 years to detect testicular cancer.
SIGNS and SYMPTOMS
Pain may be an early symptom with some cancers such as bone cancers or testicular cancer.
Long-term constipation, diarrhea, or a change in the size of the stool may be a sign of colon cancer.
Pain with urination, blood in the urine, or a change in bladder function (such as more frequent or less frequent urination) could be related to bladder or prostate cancer.
Skin cancers may bleed and look like sores that do not heal.
A long-lasting sore in the mouth could be an oral cancer and should be dealt with right away, especially in patients who smoke, chew tobacco, or frequently drink alcohol.
Sores on the penis or vagina may either be signs of infection or an early cancer, and should not be overlooked.
Unusual bleeding can happen in either early or advanced cancer.
Blood in the sputum (phlegm) may be a sign of lung cancer.
Blood in the stool (or a dark or black stool) could be a sign of colon or rectal cancer.
Blood in the urine may be a sign of bladder or kidney cancer.
A bloody discharge from the nipple may be a sign of breast cancer.
Many cancers can be felt through the skin, mostly in the breast, testicle, lymph nodes (glands), and the soft tissues of the body. A lump or thickening may be an early or late sign of cancer.
While they commonly have other causes, indigestion or swallowing problems may be a sign of cancer of the esophagus, stomach, or pharynx (throat).
A cough that does not go away may be a sign of lung cancer.
A cancer may be suspected for a variety of reasons, but the definitive diagnosis of most malignancies must be confirmed by histological examination of the cancerous cells by a pathologist.
TREATMENT
Once diagnosed, cancer is usually treated with a combination of surgery, chemotherapy and radiotherapy.
Radiation therapy may be used to treat almost every type of solid tumor, including cancers of the brain, breast, cervix, larynx, lung, pancreas, prostate, skin, stomach, uterus, or soft tissue sarcomas.
Most forms of chemotherapy target all rapidly dividing cells and are not specific for cancer cells, although some degree of specificity may come from the inability of many cancer cells to repair DNA damage, while normal cells generally can.
Contemporary methods for generating an immune response against tumours include intravesical BCG immunotherapy for superficial bladder cancer, and use of interferons and other cytokines to induce an immune response in renal cell carcinoma and melanoma patients.
Pain medication, such as morphine and oxycodone, and anti-emetics, drugs to suppress nausea and vomiting, are very commonly used in patients with cancer-related symptoms. transmission and disease.
Advances in cancer research have made a vaccine designed to prevent cancer available. The vaccine protects against four HPV types, which together cause 70% of cervical cancers and 90% of genital warts.
The consensus on diet and cancer is that obesity increases the risk of developing cancer. The cancer-fighting components of food are also proving to be more numerous and varied than previously understood, so patients are increasingly being advised to consume fresh, unprocessed fruits and vegetables for maximal health benefits.
Article Source: http://www.articlesbase.com/cancer-articles/an-overview-of-cancer-427004.html
Breast Cancer Treatment: Get it in India
Now day’s availability of high quality medical treatment facilities and most experienced cancer surgeons makes it possible to get breast cancer treatment
done without any risk and at very low cost. Indian cancer surgery hospitals provide breast cancer treatment at very low cost as compared to the cost of the breast cancer surgery in abroad cancer surgery hospitals. The cancer surgery hospitals in India are at Delhi, Hyderabad, Pune, Mumbai and Chennai. The medical infrastructure of Indian cancer surgery hospitals is world-class and the clinical care taken by them is best that’s why many abroad patients are getting attracted to India for getting their breast cancer treatment done from Indian cancer surgery hospitals at low cost. Because of the low cost of treatment and high success rate of breast cancer treatment in India, many abroad patients are getting attracted to India for their breast cancer treatment.
Breast cancer is a cancer that starts in the cells of the breast in men and women. Worldwide, breast cancer is the second most common type of cancer after lung cancer and the fifth most common cause of cancer death. Worldwide, breast cancer is by far the most common cancer amongst women, with an incidence rate more than twice that of colorectal cancer and cervical cancer and about three times that of lung cancer. However breast cancer mortality worldwide is just 25% greater than that of lung cancer in women. The incidence of breast cancer varies greatly around the world, being lower in less-developed countries and greatest in the more-developed countries. Women in the United States have the highest incidence rates of breast cancer in the world; breast cancer is the most common cancer and the second-most common cause of cancer death. Now days across the world, both incidence and death rates for breast cancer have been declining in the last few years because of the availability of high quality medical treatment facilities worldwide. Because the breast is composed of identical tissues in males and females, breast cancer also occurs in males. Incidences of breast cancer in men are very much less common than in women, but men with breast cancer are considered to have the same statistical survival rates as women. The first symptom or subjective sign, of breast cancer is typically a lump that feels different than the surrounding breast tissue. Lumps found in lymph nodes located in the armpits and/or collarbone can also indicate breast cancer. Indications of breast cancer other than a lump may include changes in breast size or shape, skin dimpling, nipple inversion, or spontaneous single-nipple discharge. Pain is an unreliable tool in determining the presence of breast cancer, but may be indicative of other breast-related health issues such as mastodynia. When breast cancer cells invade the dermal lymphatics, small lymph vessels in the skin of the breast, its presentation can resemble skin inflammation and thus is known as inflammatory breast cancer (IBC). Symptoms of inflammatory breast cancer include pain, swelling, warmth and redness throughout the breast, as well as an orange peel texture to the skin referred to as peau d'orange. Occasionally, breast cancer presents as metastatic disease, that is, cancer that has spread beyond the original organ. Metastatic breast cancer will cause symptoms that depend on the location of metastasis. More common sites of metastasis include bone, liver, lung and brain. Unexplained weight loss can occasionally herald an occult breast cancer, as can symptoms of fevers or chills. Bone or joint pains can sometimes be manifestations of metastatic breast cancer, as can jaundice or neurological symptoms. These symptoms are "non-specific," meaning they can also be manifestations of many other illnesses. With breast cancer surgery this disorder can be completely overcome. As the surgical procedure of breast cancer is very complex thus it requires an expert surgeon for the treatment.
Medical tourism in India provides best treatment facilities to abroad patients for which they are coming to India. The main aim of medical tourism in India is the provision of best clinical care of abroad patients for which they are coming India. Medical tourism in India provides very good assistance to abroad patients in getting their treatment done from India at very low cost. Breast cancer surgery in India is in high demand now days by the US patients due to availability of world class cancer treatment facilities at very low cost and with best clinical care. Indian cancer surgery hospitals provide most advanced surgical techniques for breast cancer surgery in India. For further details of breast cancer surgery in India at low cost visit: - http://www.forerunnershealthcare.com and mail us at enquiry@forerunnershealthcare.com
Article Source: http://www.articlesbase.com/cancer-articles/breast-cancer-treatment-get-it-in-india-488817.html
done without any risk and at very low cost. Indian cancer surgery hospitals provide breast cancer treatment at very low cost as compared to the cost of the breast cancer surgery in abroad cancer surgery hospitals. The cancer surgery hospitals in India are at Delhi, Hyderabad, Pune, Mumbai and Chennai. The medical infrastructure of Indian cancer surgery hospitals is world-class and the clinical care taken by them is best that’s why many abroad patients are getting attracted to India for getting their breast cancer treatment done from Indian cancer surgery hospitals at low cost. Because of the low cost of treatment and high success rate of breast cancer treatment in India, many abroad patients are getting attracted to India for their breast cancer treatment.
Breast cancer is a cancer that starts in the cells of the breast in men and women. Worldwide, breast cancer is the second most common type of cancer after lung cancer and the fifth most common cause of cancer death. Worldwide, breast cancer is by far the most common cancer amongst women, with an incidence rate more than twice that of colorectal cancer and cervical cancer and about three times that of lung cancer. However breast cancer mortality worldwide is just 25% greater than that of lung cancer in women. The incidence of breast cancer varies greatly around the world, being lower in less-developed countries and greatest in the more-developed countries. Women in the United States have the highest incidence rates of breast cancer in the world; breast cancer is the most common cancer and the second-most common cause of cancer death. Now days across the world, both incidence and death rates for breast cancer have been declining in the last few years because of the availability of high quality medical treatment facilities worldwide. Because the breast is composed of identical tissues in males and females, breast cancer also occurs in males. Incidences of breast cancer in men are very much less common than in women, but men with breast cancer are considered to have the same statistical survival rates as women. The first symptom or subjective sign, of breast cancer is typically a lump that feels different than the surrounding breast tissue. Lumps found in lymph nodes located in the armpits and/or collarbone can also indicate breast cancer. Indications of breast cancer other than a lump may include changes in breast size or shape, skin dimpling, nipple inversion, or spontaneous single-nipple discharge. Pain is an unreliable tool in determining the presence of breast cancer, but may be indicative of other breast-related health issues such as mastodynia. When breast cancer cells invade the dermal lymphatics, small lymph vessels in the skin of the breast, its presentation can resemble skin inflammation and thus is known as inflammatory breast cancer (IBC). Symptoms of inflammatory breast cancer include pain, swelling, warmth and redness throughout the breast, as well as an orange peel texture to the skin referred to as peau d'orange. Occasionally, breast cancer presents as metastatic disease, that is, cancer that has spread beyond the original organ. Metastatic breast cancer will cause symptoms that depend on the location of metastasis. More common sites of metastasis include bone, liver, lung and brain. Unexplained weight loss can occasionally herald an occult breast cancer, as can symptoms of fevers or chills. Bone or joint pains can sometimes be manifestations of metastatic breast cancer, as can jaundice or neurological symptoms. These symptoms are "non-specific," meaning they can also be manifestations of many other illnesses. With breast cancer surgery this disorder can be completely overcome. As the surgical procedure of breast cancer is very complex thus it requires an expert surgeon for the treatment.
Medical tourism in India provides best treatment facilities to abroad patients for which they are coming to India. The main aim of medical tourism in India is the provision of best clinical care of abroad patients for which they are coming India. Medical tourism in India provides very good assistance to abroad patients in getting their treatment done from India at very low cost. Breast cancer surgery in India is in high demand now days by the US patients due to availability of world class cancer treatment facilities at very low cost and with best clinical care. Indian cancer surgery hospitals provide most advanced surgical techniques for breast cancer surgery in India. For further details of breast cancer surgery in India at low cost visit: - http://www.forerunnershealthcare.com and mail us at enquiry@forerunnershealthcare.com
Article Source: http://www.articlesbase.com/cancer-articles/breast-cancer-treatment-get-it-in-india-488817.html
Signs and Symptoms of Cancer
A symptom is an indication of disease, illness, injury, or that something is not right in the body. Symptoms are felt or noticed by a person, but may not easily be noticed by anyone else. For example, chills, weakness, achiness, shortness of breath, and a cough may be symptoms of pneumonia. A sign is also an indication that something is not right in the body. But signs are defined as things that can be seen by a doctor, nurse, or other health care professional. Fever, rapid breathing rate, and abnormal breathing sounds heard through a stethoscope may be signs of pneumonia.
Having one symptom or sign may not give enough information to suggest a cause. For example, a rash in a child could be a symptom of a number of things including poison ivy, an infectious disease like measles, an infection limited to the skin, or a food allergy. But if the rash is seen along with other signs and symptoms like a high fever, chills, achiness, and a sore throat, then a doctor can get a better picture of the illness. In many cases, a patient's signs and symptoms do not give enough clues by themselves for the doctor to figure out the cause of an illness. Then medical tests, such as x-rays, blood tests, or a biopsy may be needed.
Cancer is a group of diseases that may cause almost any sign or symptom. The signs and symptoms will depend on where the cancer is, the size of the cancer, and how much it affects the nearby organs or structures. If a cancer spreads (metastasizes), then symptoms may appear in different parts of the body. As a cancer grows, it begins to push on nearby organs, blood vessels, and nerves. This pressure creates some of the signs and symptoms of cancer. If the cancer is in a critical area, such as certain parts of the brain, even the smallest tumor can cause early symptoms.
But sometimes cancers start in places where it does not cause any symptoms until the cancer has grown quite large. Pancreas cancers, for example, do not usually grow large enough to be felt from the outside of the body. Some pancreatic cancers do not cause symptoms until they begin to grow around nearby nerves (this causes a backache). Others grow around the bile duct, which blocks the flow of bile and leads to a yellowing of the skin known as jaundice. By the time a pancreatic cancer causes these signs or symptoms, it has usually reached an advanced stage.
A cancer may also cause symptoms such as fever, fatigue, or weight loss. This may be because cancer cells use up much of the body’s energy supply or release substances that change the body’s metabolism. Or the cancer may cause the immune system to react in ways that produce these symptoms. Sometimes, cancer cells release substances into the bloodstream that cause symptoms not usually thought to result from cancers. For example, some cancers of the pancreas can release substances which cause blood clots to develop in veins of the legs. Some lung cancers make hormone-like substances that affect blood calcium levels, affecting nerves and muscles and causing weakness and dizziness.
Treatment is most successful when cancer is found as early as possible. Finding cancer early usually means it can be treated while it is still small and is less likely to have spread to other parts of the body. This often means a better chance for a cure, especially if initial treatment is to be surgery. A good example of the importance of finding cancer early is melanoma skin cancer. Skin cancer can be easy to remove if it has not grown deep into the skin, and the 5-year survival rate (percentage of people living at least 5 years after diagnosis) at this stage is nearly 100%. But once melanoma has spread to other parts of the body the survival rate drops dramatically.
Sometimes people ignore symptoms either because they do not know that the symptoms could mean something is wrong or because they are frightened by what they might mean and don't want to seek medical help. General symptoms, such as fatigue, are more likely to have a cause other than cancer and can seem unimportant, especially if they have an obvious cause or only last a short time. In a similar way, a person may reason that a more specific symptom like a breast mass is probably a cyst that will go away by itself. But neither of these symptoms should be discounted or overlooked, especially if they have been present for a long time or are getting worse.
Most likely, any symptoms you may have will not be caused by cancer, but it’s important to have them checked out by your doctor, just in case. If cancer is not the cause, your doctor can help figure out what is and treat it, if needed. In some cases it is possible to detect some cancers before symptoms occur. The American Cancer Society and other health groups encourage the early detection of certain cancers before symptoms occur by recommending a cancer-related check-up and specific tests for people who do not have any symptoms. Keep in mind, however, that these recommended tests do not decrease the importance of reporting any symptoms to your doctor.
It is important to know what some of the general (non-specific) signs and symptoms of cancer are, but remember that having any of these does not mean that you have cancer. There are many other conditions that can cause these signs and symptoms, too. Most people with cancer will lose weight at some time with their disease. An unexplained (unintentional) weight loss of 10 pounds or more may be the first sign of cancer, particularly cancers of the pancreas, stomach, esophagus, or lung.
Fever is very common with cancer, but is more often seen in advanced disease. Almost all patients with cancer will have fever at some time, especially if the cancer or its treatment affects the immune system and makes it harder for the body to fight infection. Less often, fever may be an early sign of cancer, such as with leukemia or lymphoma. Fatigue may be an important symptom as cancer progresses. It may happen early, though, in cancers such as with leukemia, or if the cancer is causing an ongoing loss of blood, as in some colon or stomach cancers. Pain may be an early symptom with some cancers such as bone cancers or testicular cancer. But most often pain is a symptom of advanced disease. Along with cancers of the skin, some internal cancers can cause skin signs that can be seen. These changes include the skin looking darker (hyper pigmentation), yellow (jaundice), or red (erythema); itching; or excessive hair growth.Along with the above general symptoms, you should watch for the following common symptoms, which could be an indication of cancer. Again, there may be other causes for each of these, but it is important to bring them to your doctor’s attention as soon as possible so that they can be investigated.
Long-term constipation, diarrhea, or a change in the size of the stool may be a sign of colon cancer. Pain with urination, blood in the urine, or a change in bladder function (such as more frequent or less frequent urination) could be related to bladder or prostate cancer. Any changes in bladder or bowel function should be reported to your doctor. Skin cancers may bleed and look like sores that do not heal. A long-lasting sore in the mouth could be an oral cancer and should be dealt with right away, especially in patients who smoke, chew tobacco, or frequently drink alcohol. Sores on the penis or vagina may either be signs of infection or an early cancer, and should not be overlooked.
Unusual bleeding can happen in either early or advanced cancer. Blood in the sputum (phlegm) may be a sign of lung cancer. Blood in the stool (or a dark or black stool) could be a sign of colon or rectal cancer. Cancer of the cervix or the endometrium (lining of the uterus) can cause vaginal bleeding. Blood in the urine may be a sign of bladder or kidney cancer. A bloody discharge from the nipple may be a sign of breast cancer. Many cancers can be felt through the skin, mostly in the breast, testicle, lymph nodes (glands), and the soft tissues of the body. A lump or thickening may be an early or late sign of cancer. Any lump or thickening should be reported to your doctor, especially if you’ve just discovered it or noticed it has grown in size.
While they commonly have other causes, indigestion or swallowing problems may be a sign of cancer of the esophagus, stomach, or pharynx (throat). Any wart, mole, or freckle that changes in color, size, or shape, or loses its definite borders should be reported to your doctor without delay. The skin lesion may be a melanoma which, if diagnosed early, can be treated successfully. A cough that does not go away may be a sign of lung cancer. Hoarseness can be a sign of cancer of the larynx (voice box) or thyroid. While the signs and symptoms listed above are the more common ones seen with cancer, there are many others that are less common and are not listed here. If you notice any major changes in the way your body functions or the way you feel, especially if it lasts for a long time or gets worse, let your doctor know. If it has nothing to do with cancer, your doctor can investigate it and treat it, if needed. If it is cancer, you'll give yourself the best chance to have it treated early, when treatment is most likely to be effective.
Article Source: http://www.articlesbase.com/diseases-and-conditions-articles/signs-and-symptoms-of-cancer-512862.html
Having one symptom or sign may not give enough information to suggest a cause. For example, a rash in a child could be a symptom of a number of things including poison ivy, an infectious disease like measles, an infection limited to the skin, or a food allergy. But if the rash is seen along with other signs and symptoms like a high fever, chills, achiness, and a sore throat, then a doctor can get a better picture of the illness. In many cases, a patient's signs and symptoms do not give enough clues by themselves for the doctor to figure out the cause of an illness. Then medical tests, such as x-rays, blood tests, or a biopsy may be needed.
Cancer is a group of diseases that may cause almost any sign or symptom. The signs and symptoms will depend on where the cancer is, the size of the cancer, and how much it affects the nearby organs or structures. If a cancer spreads (metastasizes), then symptoms may appear in different parts of the body. As a cancer grows, it begins to push on nearby organs, blood vessels, and nerves. This pressure creates some of the signs and symptoms of cancer. If the cancer is in a critical area, such as certain parts of the brain, even the smallest tumor can cause early symptoms.
But sometimes cancers start in places where it does not cause any symptoms until the cancer has grown quite large. Pancreas cancers, for example, do not usually grow large enough to be felt from the outside of the body. Some pancreatic cancers do not cause symptoms until they begin to grow around nearby nerves (this causes a backache). Others grow around the bile duct, which blocks the flow of bile and leads to a yellowing of the skin known as jaundice. By the time a pancreatic cancer causes these signs or symptoms, it has usually reached an advanced stage.
A cancer may also cause symptoms such as fever, fatigue, or weight loss. This may be because cancer cells use up much of the body’s energy supply or release substances that change the body’s metabolism. Or the cancer may cause the immune system to react in ways that produce these symptoms. Sometimes, cancer cells release substances into the bloodstream that cause symptoms not usually thought to result from cancers. For example, some cancers of the pancreas can release substances which cause blood clots to develop in veins of the legs. Some lung cancers make hormone-like substances that affect blood calcium levels, affecting nerves and muscles and causing weakness and dizziness.
Treatment is most successful when cancer is found as early as possible. Finding cancer early usually means it can be treated while it is still small and is less likely to have spread to other parts of the body. This often means a better chance for a cure, especially if initial treatment is to be surgery. A good example of the importance of finding cancer early is melanoma skin cancer. Skin cancer can be easy to remove if it has not grown deep into the skin, and the 5-year survival rate (percentage of people living at least 5 years after diagnosis) at this stage is nearly 100%. But once melanoma has spread to other parts of the body the survival rate drops dramatically.
Sometimes people ignore symptoms either because they do not know that the symptoms could mean something is wrong or because they are frightened by what they might mean and don't want to seek medical help. General symptoms, such as fatigue, are more likely to have a cause other than cancer and can seem unimportant, especially if they have an obvious cause or only last a short time. In a similar way, a person may reason that a more specific symptom like a breast mass is probably a cyst that will go away by itself. But neither of these symptoms should be discounted or overlooked, especially if they have been present for a long time or are getting worse.
Most likely, any symptoms you may have will not be caused by cancer, but it’s important to have them checked out by your doctor, just in case. If cancer is not the cause, your doctor can help figure out what is and treat it, if needed. In some cases it is possible to detect some cancers before symptoms occur. The American Cancer Society and other health groups encourage the early detection of certain cancers before symptoms occur by recommending a cancer-related check-up and specific tests for people who do not have any symptoms. Keep in mind, however, that these recommended tests do not decrease the importance of reporting any symptoms to your doctor.
It is important to know what some of the general (non-specific) signs and symptoms of cancer are, but remember that having any of these does not mean that you have cancer. There are many other conditions that can cause these signs and symptoms, too. Most people with cancer will lose weight at some time with their disease. An unexplained (unintentional) weight loss of 10 pounds or more may be the first sign of cancer, particularly cancers of the pancreas, stomach, esophagus, or lung.
Fever is very common with cancer, but is more often seen in advanced disease. Almost all patients with cancer will have fever at some time, especially if the cancer or its treatment affects the immune system and makes it harder for the body to fight infection. Less often, fever may be an early sign of cancer, such as with leukemia or lymphoma. Fatigue may be an important symptom as cancer progresses. It may happen early, though, in cancers such as with leukemia, or if the cancer is causing an ongoing loss of blood, as in some colon or stomach cancers. Pain may be an early symptom with some cancers such as bone cancers or testicular cancer. But most often pain is a symptom of advanced disease. Along with cancers of the skin, some internal cancers can cause skin signs that can be seen. These changes include the skin looking darker (hyper pigmentation), yellow (jaundice), or red (erythema); itching; or excessive hair growth.Along with the above general symptoms, you should watch for the following common symptoms, which could be an indication of cancer. Again, there may be other causes for each of these, but it is important to bring them to your doctor’s attention as soon as possible so that they can be investigated.
Long-term constipation, diarrhea, or a change in the size of the stool may be a sign of colon cancer. Pain with urination, blood in the urine, or a change in bladder function (such as more frequent or less frequent urination) could be related to bladder or prostate cancer. Any changes in bladder or bowel function should be reported to your doctor. Skin cancers may bleed and look like sores that do not heal. A long-lasting sore in the mouth could be an oral cancer and should be dealt with right away, especially in patients who smoke, chew tobacco, or frequently drink alcohol. Sores on the penis or vagina may either be signs of infection or an early cancer, and should not be overlooked.
Unusual bleeding can happen in either early or advanced cancer. Blood in the sputum (phlegm) may be a sign of lung cancer. Blood in the stool (or a dark or black stool) could be a sign of colon or rectal cancer. Cancer of the cervix or the endometrium (lining of the uterus) can cause vaginal bleeding. Blood in the urine may be a sign of bladder or kidney cancer. A bloody discharge from the nipple may be a sign of breast cancer. Many cancers can be felt through the skin, mostly in the breast, testicle, lymph nodes (glands), and the soft tissues of the body. A lump or thickening may be an early or late sign of cancer. Any lump or thickening should be reported to your doctor, especially if you’ve just discovered it or noticed it has grown in size.
While they commonly have other causes, indigestion or swallowing problems may be a sign of cancer of the esophagus, stomach, or pharynx (throat). Any wart, mole, or freckle that changes in color, size, or shape, or loses its definite borders should be reported to your doctor without delay. The skin lesion may be a melanoma which, if diagnosed early, can be treated successfully. A cough that does not go away may be a sign of lung cancer. Hoarseness can be a sign of cancer of the larynx (voice box) or thyroid. While the signs and symptoms listed above are the more common ones seen with cancer, there are many others that are less common and are not listed here. If you notice any major changes in the way your body functions or the way you feel, especially if it lasts for a long time or gets worse, let your doctor know. If it has nothing to do with cancer, your doctor can investigate it and treat it, if needed. If it is cancer, you'll give yourself the best chance to have it treated early, when treatment is most likely to be effective.
Article Source: http://www.articlesbase.com/diseases-and-conditions-articles/signs-and-symptoms-of-cancer-512862.html
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